ArticleIndian journal of endocrinology and metabolism
Differences in Endocrine Manifestations in HIV-Infected Subjects on Anti-Retroviral Therapy (ART) Versus not on ART.
Article in Indian journal of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Few studies have examined endocrine dysfunction associated with anti-retroviral therapy (ART) for human immunodeficiency virus (HIV) infection. The aim is to assess various endocrine changes, including vitamin D metabolism and glycaemic status, of subjects on ART versus not on ART (non-ART) and to assess the relationship with CD4 + T helper cell count. Methods: Ninety-three HIV-positive subjects were selected and underwent thyroid function tests (thyroid stimulating hormone and free thyroxine). Fasting plasma glucose, glycated haemoglobin, Cortisol, ACTH, total testosterone (male), follicle stimulating hormone, luteinising hormone, Prolactin, 25(OH) D, intact parathyroid hormone, calcium, phosphorus, albumin and magnesium levels, and CD4+ T-helper cell counts were performed in all subjects. Results: There was a positive correlation between vitamin D and CD4 count ( Conclusion: Our study showed endocrine dysfunction more common in patients who received ART than in those who did not. Severe vitamin D deficiency was also common in the ART group. Serum vitamin D levels were positively correlated with CD4+ T cell counts.
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