Evidence map›Paper›PMID 41918555›Full record

ReviewRSC sustainability2026

A concept for the molecular design of readily treatable chemicals.

Gabriel Sigmund, Sanne J Smith, Anett Georgi, Thomas V Wagner, Mohamed Ateia, Benedikt M Aumeier, Jouke E Dykstra, Holger V Lutze, Michael Neumann, Nora B Sutton and 2 more

Abstract readReview
In one paragraph

Review in RSC sustainability, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Gabriel SigmundEnvironmental Technology, Wageningen University P. O. Box 17 6700 AA Wageningen The Netherlands gabriel.sigmund@wur.nl.ORCID https://orcid.org/0000-0003-2068-0878
Sanne J SmithDepartment of Water Management, Delft University of Technology Stevinweg 1 2628 CN Delft The Netherlands.ORCID https://orcid.org/0000-0002-3487-0528
Anett GeorgiDepartment of Technical Biogeochemistry, Helmholtz Centre for Environmental Research - UFZ Leipzig Germany.ORCID https://orcid.org/0000-0002-2941-1255
Thomas V WagnerEnvironmental Technology, Wageningen University P. O. Box 17 6700 AA Wageningen The Netherlands gabriel.sigmund@wur.nl.ORCID https://orcid.org/0000-0001-8540-0123
Mohamed AteiaDepartment of Chemical and Biomolecular Engineering, Rice University Houston TX USA.ORCID https://orcid.org/0000-0002-3524-5513
Benedikt M AumeierChair of Urban Water Systems Engineering, Technical University of Munich Am Coulombwall 3 85748 Garching Germany.ORCID https://orcid.org/0000-0003-2167-4066
Jouke E DykstraEnvironmental Technology, Wageningen University P. O. Box 17 6700 AA Wageningen The Netherlands gabriel.sigmund@wur.nl.
Holger V LutzeTechnical University of Darmstadt, Institute IWAR, Chair of Environmental Analytics and Pollutants Franziska-Braun-Straße 7 64287 Darmstadt Germany.
Michael NeumannGerman Environment Agency, Section IV 2.3 Chemicals Wörlitzer Platz 1 06844 Dessau-Roßlau Germany.
Nora B SuttonEnvironmental Technology, Wageningen University P. O. Box 17 6700 AA Wageningen The Netherlands gabriel.sigmund@wur.nl.
Daniel ZahnDepartment of Environmental Analytical Chemistry, Helmholtz Centre for Environmental Research - UFZ Leipzig Germany.
Zhanyun WangEmpa-Swiss Federal Laboratories for Materials Science and Technology, Technology and Society Laboratory 9014 St. Gallen Switzerland.ORCID https://orcid.org/0000-0001-9914-7659

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Existing chemicals assessment and management approaches focus on chemical behavior in the natural environment and humans, including using chemical-specific inherent properties such as persistence (P), bioaccumulation potential (B), and mobility (M). To prevent chemical pollution, concepts such as safe-by-design and benign-by-design consider P, B, M, toxicity, and other hazardous properties when selecting existing chemicals or developing new ones. However, certain applications rely on chemical properties that inherently conflict with safe-by-design (

Identifiers

PMID41918555
PMCPMC13034026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.