Evidence map›Paper›PMID 41918189›Full record

ArticleJournal of breast cancer2026

Solitary Fibrous Tumors of the Breast: Report of Two Cases and Systematic Review.

Billy Ho Hung Cheung, Sha Zhao, Ava Kwong, Maximus Yeung

Abstract read
In one paragraph

Article in Journal of breast cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Billy Ho Hung CheungDivision of Breast Surgery, Department of Surgery, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong.ORCID https://orcid.org/0000-0002-8843-7893
Sha ZhaoSchool of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong.ORCID https://orcid.org/0009-0000-2422-885X
Ava KwongDivision of Breast Surgery, Department of Surgery, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong.ORCID https://orcid.org/0000-0002-6968-9489
Maximus YeungDepartment of Pathology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong. mcfyeung@pathology.hku.hk.ORCID https://orcid.org/0000-0001-9942-0109

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSolitary fibrous tumors (SFTs) are rare mesenchymal neoplasms most commonly found in the pleura, but may also arise in other locations. Breast SFTs are extremely rare and infrequently reported. Descriptive data on the clinical, radiological, and pathological characteristics of breast SFTs are important for improving understanding of the disease, treatment strategies, and follow-up planning.

methodsThe pathology databases of major surgical centers in Hong Kong, covering January 2020 to June 2023, were assessed to identify cases with a diagnostic code for SFT. A systematic literature search was conducted to identify all reported cases of breast SFTs. The search was performed using multiple scientific databases, including PubMed, Web of Science, Embase, and Scopus.

resultsWe report two cases of breast SFTs in Chinese female patients without a family history of breast cancer. Both patients presented with a palpable breast lump that appeared suspicious on ultrasonography (Breast Imaging-Reporting and Data System 4). Both patients underwent surgical excision of the lesions with negative margins. The diagnosis of SFT was established based on immunohistochemical findings in tumor samples obtained from surgical excision. No signs of recurrence were observed at follow-up. A literature review yielded 62 cases of breast SFT, including the two cases reported here. No clinically distinguishing features have been reported in the literature, other than that the majority of patients presented with a mass. SFTs were more commonly found in females (n = 47) than in males (n = 15), although the female-to-male ratio was lower than that observed in other breast cancers.

conclusionWe describe two patients with breast SFTs, together with a comprehensive literature review, to contribute to the currently limited knowledge of this disease. A complete picture of the clinical, radiological, and pathological features of breast SFTs could help improve understanding of the condition and guide appropriate management.

Indexed as

Breast NeoplasmsHemangiopericytomaSolitary Fibrous Tumors

Identifiers

PMID41918189
PMCPMC13338610

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.