ArticleJournal of cosmetic dermatology2026
The Value of High-Frequency Ultrasound and Color Doppler Flow Imaging in Assessing the Efficacy of Moderate-to-Severe Acne Vulgaris: A Prospective Single-Arm Study.
Article in Journal of cosmetic dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Multimodal Non-Invasive Skin Imaging in Dermatology: Current Modalities, Clinical Applications, and Future Integration.Diagnostics (Basel, Switzerland) · 2026Review
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Authors and funding
8 authors.
Funding
Abstract
objectiveThis study aimed to investigate the value of non-invasive skin detection techniques for the therapeutic assessment of moderate-to-severe acne vulgaris.
methodsIn this study, we collected patients with moderate-to-severe acne vulgaris who attended the Department of Dermatology at the First Affiliated Hospital of Guilin Medical University between October 2021 and December 2022, and analyzed their high-frequency ultrasound (HFUS) and color Doppler flow imaging (CDFI) characteristics at the Weekend 0 (T0), Weekend 4 (T1), and Weekend 12 (T2) of their treatment.
resultsA total of 30 patients with moderate-to-severe acne vulgaris [mean age 21.1 ± 3.4 years; 14 males (46.7%), 16 females (53.3%)] were enrolled. HFUS assessment revealed improvements (p < 0.05) in multiple parameters following treatment. Prior to treatment, there was perfect agreement (κ = 1.0) between the Pillsbury clinical grading and the SSSA ultrasound grading in all 30 patients (100%). Among the 30 patients who completed the 12-week follow-up, post-treatment ultrasound grading was higher than the clinical Pillsbury grading in 17 cases (56.7%). Agreement between the two grading methods post-treatment was poor (κ = 0.3, p = 0.645, 95% CI: -0.17, 0.77), though statistical significance was limited by sample size.
conclusionHFUS effectively visualizes deep acne lesions (nodules/cysts). Although ultrasound grading demonstrates slower severity reduction than clinical assessment, it provides more objective severity evaluation. CDFI enhances hemodynamic analysis through real-time flow visualization. Combined HFUS/CDFI enables enhanced severity and prognostic assessment in moderate-to-severe acne vulgaris.
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