Evidence map›Paper›PMID 41918049›Full record

ArticleInternational journal of retina and vitreous2026

Relaxing retinectomy and autologous retinal transplant for complex retinal detachment with macular hole: a case series.

Rami Madani, Armin Wolf, Jad Madani, Michael F Ward, Matthew Cohen, Ferris Bayasi, Tarek Alasil

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Article in International journal of retina and vitreous, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Rami MadaniWestern Michigan University Homer Stryker MD School of Medicine, Kalamazoo, MI, USA.
Armin WolfDepartment of Ophthalmology, University Hospital Ulm, Ulm, Germany.
Jad MadaniDepartment of Ecology and Evolutionary Biology, University of California, Los Angeles, 612 Charles E. Young Drive South, Los Angeles, CA, 90095, USA. Jad2007@g.ucla.edu.
Michael F WardVitreoretinal Surgery, Retina Institute of California, Pasadena, CA, USA.
Matthew CohenWestern Michigan University Homer Stryker MD School of Medicine, Kalamazoo, MI, USA.
Ferris BayasiKresge Eye Institute, Detroit Medical Center, Detroit, MI, USA.
Tarek AlasilVitreoretinal Surgery, Retina Institute of California, Pasadena, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo describe the surgical techniques for transplantation of an autologous retinal graft in cases of chronic retinal detachment with proliferative vitreoretinopathy and full-thickness macular hole.

methodsDescriptive case series of three consecutive patients (1 woman and 2 men; ages 60, 60, and 61) who underwent pars plana vitrectomy with peeling of proliferative vitreoretinopathy membranes, followed by relaxing retinectomy, where a notch was created to harvest a full-thickness neurosensory retinal graft. Perfluoro-n-octane was injected to flatten the retinectomy edges and stabilize the graft, which was then separated from the retinectomy edge and gently mobilized under Perfluoro-n-octane using a finesse loop to plug the macular hole. Endolaser was applied to the retinectomy edge under Perfluoro-n-octane, followed by a controlled Perfluoro-n-octane –air exchange and silicone oil (5000 cSt) infusion.

resultsPrimary outcomes were anatomical macular hole closure and retinal reattachment; visual outcomes were assessed by postoperative visual acuity, exam and imaging. Initial visual acuity ranged from light perception to hand motion. Postoperatively, visual acuity improved from light perception and hand motion to 20/400 and 20/200; the retina remained attached, and the macular hole was successfully closed, with the autologous retinal transplant integrating into the surrounding retinal tissue.

conclusionsAutologous retinal transplant, coupled with a relaxing retinectomy, may present a promising strategy for closing macular holes and improving visual acuity in cases of complex retinal detachment with proliferative vitreoretinopathy. We show that this procedure can be performed unimanually, potentially reducing technical demands in such cases.

Indexed as

Autologous retinal transplantMacular holeProliferative vitreoretinopathyRelaxing retinectomyRetinal detachmentRhegmatogenous retinal detachment

Identifiers

PMID41918049
PMCPMC13159287

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