Evidence map›Paper›PMID 41917997›Full record

ReviewParticle and fibre toxicology2026

A comprehensive review on the role of PM2.5 in modulating transplant immunity and graft survival.

Muhammad Adil Malik, Quan Zhuang, Junjie Huang, Xu Cao

Abstract readReview
In one paragraph

Review in Particle and fibre toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Muhammad Adil MalikThird Xiangya Hospital, Central South University, Changsha, Hunan, China.ORCID http://orcid.org/0009-0006-3028-4093
Quan ZhuangThird Xiangya Hospital, Central South University, Changsha, Hunan, China. zhuangquansteven@163.com.
Junjie HuangThird Xiangya Hospital, Central South University, Changsha, Hunan, China. hjjhuang@hotmail.com.
Xu CaoThird Xiangya Hospital, Central South University, Changsha, Hunan, China. hughcaoxu@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organ transplantation is an indispensable therapeutic approach for patients experiencing end-stage organ failure. Despite ongoing advancements and refinements in immunosuppressive therapies aimed at mitigating graft rejection and enhancing graft longevity, environmental influences including particulate matter 2.5 (PM2.5) have emerged as significant determinants of post-transplant health. PM2.5, a prevalent environmental contaminant, is particularly concerning due to its widespread presence and detrimental biological effects. Notably, the living environment of transplant recipients further exacerbates the complexity of post-transplant outcomes. Evaluating findings from recent investigations, this review delves into the influence of PM2.5 exposure on the immune system. The findings identify its capacity to provoke systemic inflammation, disrupt cytokine profiles, and compromise immune tolerance mechanisms. Such immune dysfunction poses direct risks to graft integrity, with potential implications for both graft health and the prospects of achieving long-term graft survival in affected patients.

Indexed as

Air PollutantsGraft RejectionGraft SurvivalOrgan TransplantationParticulate MatterAnimalsHumansAir PollutantsParticulate MatterChronic rejectionEnvironmental pollutionImmune toleranceImmunosuppressive therapyMacrophagesParticulate matter 2.5Systemic inflammation

Identifiers

PMID41917997
PMCPMC13036968

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.