ArticleBMC veterinary research2026
Evaluation of the effects of a single bolus of cisatracurium as part of an anesthetic protocol in cats undergoing orthopedic surgery.
Article in BMC veterinary research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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8 authors.
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Abstract
Non-depolarizing neuromuscular blocking agents (NMBAs) are commonly used in human anesthesia but remain uncommon in veterinary medicine. This study evaluated the effects of 0.5 mg/kg cisatracurium IV on muscle relaxation, cardiovascular variables and postoperative pain in cats undergoing orthopedic surgery. Twenty-four cats were randomly assigned to a control group (Group C) or a treatment group receiving cisatracurium (Group M) immediately after induction. Neuromuscular function was monitored using a calibrated train-of-four (TOF) device. Postoperative pain was assessed with the short form of the Glasgow Feline Composite Measure Pain Scale (CMPS-Feline). The mean time to suppression of muscle contraction was 2.6 ± 0.8 min, with peak suppression (90%) at 3.0 ± 0.7 min, a mean duration of 23.3 ± 4.4 min, and complete recovery at 27.3 ± 8.6 min. Group M required lower sevoflurane concentrations to maintain anesthesia compared to Group C (p < 0.001) and had a shorter mean surgical time (25.3 ± 3 min vs. 31.5 ± 4 min; p < 0.001). Pain scores were also lower in Group M (p = 0.01). These findings demonstrate that cisatracurium effectively induces neuromuscular block (NMB) and improves surgical conditions, resulting in lower postoperative pain scores in cats undergoing femoral fracture repair.
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