Evidence map›Paper›PMID 41917921›Full record

ArticleBMC oral health2026

Effect of 4-META and 10-MDP primers on the adhesion of resin cement to conventional and translucent polycrystalline dental ceramics.

Nathalia Elen Barbosa Dos Santos, Tainah Oliveira Rifane, Guilherme Magalhães Ribeiro, Vitaliano Gomes de Araújo Neto, Madiana Magalhães Moreira, Victor Pinheiro Feitosa, Tan Fırat Eyüboğlu, Mutlu Özcan, Diego Martins de Paula

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Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Nathalia Elen Barbosa Dos SantosPaulo Picanço School of Dentistry, Fortaleza, Ceará, Brazil.
Tainah Oliveira RifanePaulo Picanço School of Dentistry, Fortaleza, Ceará, Brazil.
Guilherme Magalhães RibeiroPaulo Picanço School of Dentistry, Fortaleza, Ceará, Brazil.
Vitaliano Gomes de Araújo NetoDepartment of Dental Materials, Piracicaba Dental School (FOP), University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.
Madiana Magalhães MoreiraPaulo Picanço School of Dentistry, Fortaleza, Ceará, Brazil.
Victor Pinheiro FeitosaCollege of Dentistry, Operative Dentistry Department, University of Iowa, Iowa, Iowa, USA.
Tan Fırat EyüboğluFaculty of Dentistry, Department of Endodontics, Istanbul Medipol University, Cibali Mahallesi, Atatürk Bulvari, No: 27, Istanbul, 34083, Türkiye. tfeyuboglu@yahoo.com.ORCID 0000-0002-0308-9579
Mutlu ÖzcanClinic of Masticatory Disorders and Dental Biomaterials, Center for Dental Medicine, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-9623-6098
Diego Martins de PaulaPaulo Picanço School of Dentistry, Fortaleza, Ceará, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the effect of different experimental primers containing 4-methacryloxyethyl trimellitate anhydride (4-META) and 10-methacryloyloxydecyl dihydrogen phosphate (10-MDP) on microshear bond strength (µSBS) and contact angle (CA) in different generations of zirconia.

methodsTwo experimental primers were prepared: 1 wt% 10-MDP in an ethanol-water solution and 1 wt% 4-META in an acetone-water solution. A commercial primer (Clearfil Ceramic Primer Plus) served as the control. Three zirconia types (3Y-TZP, 4Y-PSZ, 5Y-PSZ) were conditioned and bonded with RelyX ARC resin cement. µSBS (n = 6) was measured after 48 h and after 5,000 thermocycles, and fracture patterns were assessed. CA measurements (n = 8) were obtained using the sessile drop method. Data were analyzed using two-way ANOVA and Tukey’s test (α = 0.05).

resultsImmediate µSBS showed no differences among primers for 3Y-TZP and 4Y-PSZ (p > 0.05), whereas 10-MDP yielded higher values on 5Y-PSZ compared with 4-META (37.04 ± 5.60 MPa vs. 28.53 ± 4.62 MPa; p = 0.028). After aging, 4-META showed significantly lower µSBS on 5Y-PSZ (8.27 ± 7.56 MPa) than 10-MDP and control (p < 0.001). For contact angle, 4-META produced lower values on 5Y-PSZ than on 3Y-TZP and 4Y-PSZ (p < 0.001), while 10-MDP had the lowest CA on 3Y-TZP (p = 0.002). Adhesive failures predominated.

conclusionsThe 10-MDP primer showed stable bonding across all zirconia types, whereas 4-META exhibited reduced bonding stability, particularly on cubic-rich zirconias. These findings highlight the importance of zirconia composition and monomer chemistry in adhesion, indicating that simplified MDP-based formulations may provide effective bonding to high-translucency zirconias.

Indexed as

Dental BondingDental PorcelainMethacrylatesResin CementsAcetoneAdhesivenessBisphenol A-Glycidyl MethacrylateDental Stress AnalysisEthanolMaterials TestingOrganophosphorus CompoundsPolyethylene GlycolsPolymethacrylic AcidsShear StrengthSolventsStress, Mechanical4-methacryloxyethyltrimellitic acid anhydrideAcetoneBisphenol A-Glycidyl MethacrylateClearfil Ceramic PrimerDental PorcelainEthanolMDP adhesion promoting monomerMethacrylatesmethacryloyloxydecyl dihydrogen phosphateOrganophosphorus CompoundsPolyethylene GlycolsPolymethacrylic AcidsRelyX ARCResin CementsSolventsWateryttria stabilized tetragonal zirconiaYttriumZirconiumzirconium oxideAdhesionCeramicsDental materialsMicroshear bond strengthPrimersProsthodtonticsZirconia

Identifiers

PMID41917921
PMCPMC13169999

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.