Evidence map›Paper›PMID 41917743›Full record

ArticlePhysiological reports2026

Characterizing airway epithelial cultures grown on permeable inserts with different pore densities.

T J F Guo, G K Singhera, J Memar Vaghri, W Y Liang, J M Leung, D R Dorscheid

Abstract read
In one paragraph

Article in Physiological reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Frontiers in microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

T J F GuoCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.ORCID https://orcid.org/0009-0007-3895-1791
G K SingheraCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
J Memar VaghriCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
W Y LiangCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
J M LeungCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
D R DorscheidCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.

Funding

Asthma CanadaBritish Columbia Lung AssociationCanadian Allergy, Asthma, and Immunology FoundationCanadian Institutes of Health Research (CIHR)Faculty of Medicine, University of British ColumbiaSt. Paul's Foundation
6 · The paper itself

Abstract

In vitro airway epithelial models, such as air-liquid interface (ALI) cultures, are widely used for disease modeling, therapeutic and toxicology testing, and studying epithelial-environmental interactions. However, it remains unknown whether the pore density of the permeable membrane inserts, on which primary human bronchial epithelial cells (HBEC) are grown, influences their morphological and differentiation characteristics. To investigate this, HBEC from seven donors were cultured on inserts with low (4 × 10

Indexed as

BronchiCell Culture TechniquesEpithelial CellsRespiratory MucosaCell DifferentiationCells, CulturedHumansPorosityair‐liquid interfaceairway epitheliumcell culturepermeable inserts

Identifiers

PMID41917743
PMCPMC13140211

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.