Evidence map›Paper›PMID 41917637›Full record

ReviewAdvances in experimental medicine and biology2026

The Influence of Exercise on the Endocrine System: Impacts on Adolescent Growth and Development.

Juliana Soares Severo, Rodrigo Soares Pereira Lima, Aureliano Machado de Oliveira, Thiago Sousa Reinaldo, Francisco Leonardo Torres-Leal, Moisés Tolentino Bento da Silva

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Juliana Soares SeveroMetabolic Diseases, Exercise and Nutrition Research Group (DOMEN), Laboratory of Metabolic Diseases Glauto Tuquarre, Department of Biophysics and Physiology, Center for Health Sciences, Federal University of Piaui, Teresina, Brazil.
Rodrigo Soares Pereira LimaMetabolic Diseases, Exercise and Nutrition Research Group (DOMEN), Laboratory of Metabolic Diseases Glauto Tuquarre, Department of Biophysics and Physiology, Center for Health Sciences, Federal University of Piaui, Teresina, Brazil.
Aureliano Machado de OliveiraMetabolic Diseases, Exercise and Nutrition Research Group (DOMEN), Laboratory of Metabolic Diseases Glauto Tuquarre, Department of Biophysics and Physiology, Center for Health Sciences, Federal University of Piaui, Teresina, Brazil.
Thiago Sousa ReinaldoMetabolic Diseases, Exercise and Nutrition Research Group (DOMEN), Laboratory of Metabolic Diseases Glauto Tuquarre, Department of Biophysics and Physiology, Center for Health Sciences, Federal University of Piaui, Teresina, Brazil.
Francisco Leonardo Torres-LealMetabolic Diseases, Exercise and Nutrition Research Group (DOMEN), Laboratory of Metabolic Diseases Glauto Tuquarre, Department of Biophysics and Physiology, Center for Health Sciences, Federal University of Piaui, Teresina, Brazil.
Moisés Tolentino Bento da SilvaLaboratory of Physiology, Center for Drug Discovery and Innovative Medicines (MedInUP) - RISE-Health: Health Research Network. Department of Immuno-Physiology and Pharmacology, School of Medicine and Biomedical Science, University of Porto (ICBAS - UP), Porto, Portugal. mtsilva@icbas.up.pt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adolescence is a critical period for growth, maturation, and endocrine regulation, during which hormonal adaptations play a key role in physical development and long-term metabolic health. Physical exercise acts as an important physiological stimulus capable of modulating several endocrine pathways involved in energy balance, appetite regulation, and cardiometabolic function. This chapter discusses the influence of exercise on the endocrine system in children and adolescents, emphasizing its effects on metabolic control, body composition, and appetite-related hormones. Evidence indicates that aerobic, resistance, and combined exercise interventions improve insulin sensitivity, reduce cardiometabolic risk factors, and promote favorable hormonal responses, even in the absence of significant weight loss. Acute exercise transiently suppresses orexigenic signals and enhances satiety-related hormones without inducing compensatory increases in energy intake, particularly in adolescents with overweight or obesity. The chapter also addresses practical considerations for exercise prescription in this population, highlighting the importance of developmentally appropriate, individualized, and supportive approaches. Overall, physical exercise represents a key non-pharmacological strategy to support endocrine balance and healthy growth during adolescence.

Indexed as

Adolescent DevelopmentEndocrine SystemExerciseAdolescentAppetite RegulationBody CompositionChildEnergy MetabolismHumansAdolescenceAppetite regulationEndocrine systemGrowth and developmentMetabolic healthPhysical exercise

Identifiers

PMID41917637

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.