Evidence map›Paper›PMID 41917512›Full record

ArticleEJNMMI radiopharmacy and chemistry2026

Redox-driven speciation and colloid formation contribute the in vivo chemistry and organ deposition of Astatine-211.

Xiaoxu Dong, Jiaojiao Li, Mumei Chen, Kaiqi Zhang, Xiaozheng Zhang, Fengling Shan, Shuai Xue, Xiao Li, Lan Zhang, Huawei Cai and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI radiopharmacy and chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiaoxu DongShanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China.
Jiaojiao LiShanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China.
Mumei ChenShanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China.
Kaiqi ZhangShanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China.
Xiaozheng ZhangShanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China.
Fengling ShanDepartment of Nuclear Medicine, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, 201399, China.
Shuai XueDepartment of Nuclear Medicine, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, 201399, China.
Xiao LiShanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China.
Lan ZhangShanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China.
Huawei CaiDepartment of Nuclear Medicine and Clinical Nuclear Medicine Research Lab, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China. huawei.cai@wchscu.cn.
Jiajun LiuDepartment of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. ljj9081@163.com.
Qingnuan LiShanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China. liqingnuan@sinap.ac.cn.

Funding

1.3.5 Project for Disciplines of Excellence, West China Hospital, Sichuan Grant No. ZYGD23016Health Science and Technology Project of Pudong Municipal Health Commission, Shanghai Grant No. PW2023B-15National Natural Science Foundation of China Youth Program, Grant No. 82202214Self-deployed Project of Shanghai Institute of Applied Physics Grant No. SINAP-QYJS-202401
6 · The paper itself

Abstract

backgroundAstatine-211 (

resultsComparative in vivo studies revealed that free

conclusionsThese results identify redox-driven speciation and subsequent hydrolysis/aggregation as key chemical processes contributing to the in vivo behavior of free

Indexed as

Astatine-211Colloid formationRadiochemical speciationRadiopharmaceutical stabilityRedox-driven speciationTargeted alpha therapy

Identifiers

PMID41917512
PMCPMC13172141

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.