Evidence map›Paper›PMID 41917351›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Methods for Defining the Role of ADAMTS1 in the Ovary.

Vinesh Dahiya, Sharmin Shila, Mohammad A Rumi

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vinesh DahiyaDepartment of Pathology and Laboratory Medicine, The University of Kansas Medical Center, Kansas City, KS, USA.
Sharmin ShilaDepartment of Pathology and Laboratory Medicine, The University of Kansas Medical Center, Kansas City, KS, USA.
Mohammad A RumiDepartment of Pathology and Laboratory Medicine, The University of Kansas Medical Center, Kansas City, KS, USA. mrumi@kumc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The protease activity of ADAMTS1 is essential for ovarian development and function. It cleaves and remodels the extracellular matrix (ECM) to accommodate growing follicles and the vascular networks. While the loss of ADAMTS1 activity affects ovulation and leads to pathological conditions like polycystic ovary syndrome (PCOS), an increased activity may result in premature ovarian failure and ovarian cancers. These findings highlight the precise action of this enzyme in maintaining normal ovarian functions. This chapter describes the methods for detecting, localizing, and determining the activity of ADAMTS1 in the ovary.

Indexed as

ADAMTS1 ProteinOvaryAnimalsExtracellular MatrixFemaleHumansMiceADAMTS1 ProteinADAMTS1Expression analysesExtracellular matrixFunctional assaysOvary

Identifiers

PMID41917351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.