Evidence map›Paper›PMID 41916900›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2026

Diagnostic Testing Patterns Influence the Detected Burden of Hypertension-Mediated Organ Damage in Hospitalized Hypertensive Patients.

The Dung Bui, Phuc Tai Le, Le Nhat Thanh Dinh, Thi Huynh Nhu Nguyen, Thi Phuong Thao Doan, Thi Thanh Huong Vo, Thi Hong Lan Nguyen, Thi Thanh Hoa Nguyen, Thi Thao Nguyen Dang, Thanh Chinh Ho and 1 more

Abstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

The Dung BuiDepartment of Cardiology, University Medical Center Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Phuc Tai LeDepartment of Cardiology, University Medical Center Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Le Nhat Thanh DinhDepartment of Cardiology, University Medical Center Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Thi Huynh Nhu NguyenDepartment of Cardiology, University Medical Center Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Thi Phuong Thao DoanDepartment of Cardiology, University Medical Center Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Thi Thanh Huong VoDepartment of Cardiology, University Medical Center Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Thi Hong Lan NguyenDepartment of Cardiology, University Medical Center Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Thi Thanh Hoa NguyenDepartment of Cardiology, University Medical Center Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Thi Thao Nguyen DangDepartment of Cardiology, University Medical Center Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Thanh Chinh HoDepartment of Cardiology, University Medical Center Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Ngoc Mai Han CaoDepartment of Cardiology, University Medical Center Ho Chi Minh City, Ho Chi Minh City, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension-mediated organ damage (HMOD) plays a central role in cardiovascular risk stratification, yet real-world implementation of guideline-recommended screening remains heterogeneous across Asian healthcare systems. We conducted a retrospective cross-sectional study of 315 hospitalized hypertensive patients admitted to a Vietnamese tertiary referral hospital between January and June 2024 to evaluate completion rates of HMOD-related investigations and the detected burden of organ damage among tested patients. Basic laboratory tests, electrocardiography, and echocardiography were performed in nearly all patients, whereas urine albumin-to-creatinine ratio testing (34.3%), fundoscopic examination (6.7%), and ankle-brachial index measurement (1.6%) were selectively utilized. Left ventricular hypertrophy was detected in 55.9% of the cohort. Among patients undergoing corresponding investigations, diagnostic yield was substantial for peripheral atherosclerosis (70.5%), albuminuria (68.5%), and cerebral white matter lesions (33.0%). Importantly, 68.5% of patients without established cardiovascular disease had evidence of at least one form of HMOD. These findings demonstrate that the apparent burden of HMOD in hospitalized hypertensive patients is strongly shaped by diagnostic testing patterns. Systematic implementation of selected high-yield investigations, particularly quantitative albuminuria assessment, may represent a pragmatic strategy to improve detection of silent organ damage in tertiary-care settings.

Indexed as

HypertensionAgedAlbuminuriaAnkle Brachial IndexCardiovascular DiseasesCross-Sectional StudiesEchocardiographyElectrocardiographyFemaleHospitalizationHumansHypertrophy, Left VentricularMaleMass ScreeningMiddle AgedRetrospective Studiescardiovascular risk stratificationcross‐sectional studydiagnostic utilizationimplementation gapsubclinical organ damage

Identifiers

PMID41916900
PMCPMC13140622

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.