ArticleLupus science & medicine2026
Pulmonary diseases in SLE: a population-based cross-sectional study.
Article in Lupus science & medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06087523 (Prevalence of Pulmonary Diseases Among Patients With Systemic Lupus Erythematosus, a Population-Based Cross-Sectional Study), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevalence of Pulmonary Diseases Among Patients With Systemic Lupus Erythematosus, a Population-Based Cross-Sectional Study
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and incidence of interstitial lung diseases in systemic lupus erythematosus: systematic review and meta-analyses.Lupus science & medicine · 2026Pooled it
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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesPulmonary diseases (PDs) in SLE are thought to be common and of clinical importance but can be difficult to diagnose. Prior studies report divergent estimates of the prevalence of PD in SLE ranging from 30% to 98%. Therefore, our primary objective was to determine the prevalence of PD in patients with SLE, through a population-based cross-sectional study. Our secondary objectives were to investigate in patients with SLE: (1) the prevalence of specific subtypes of PD, (2) pulmonary function and (3) associations between selected patient characteristics and presence of PD and subtypes of PD.
methodsWe invited adult patients with SLE who met the classification criteria and lived in Region Southern Denmark. Each participant underwent a clinical assessment, pulmonary function tests (PFTs) and a chest high-resolution CT scan (HRCT). Subsequently, participants were assessed and diagnosed according to the presence of PD and subtypes of PD at a multidisciplinary discussion.
resultsWe found PDs were prevalent in 109 (59%) of the 185 included participants, among whom interstitial lung diseases were prevalent in 22 (12%), pleural diseases in 35 (19%) and airway diseases in 70 (38%). PD and subtypes of PD were associated with decreased pulmonary function, but the PFT measures showed a low combined sensitivity and specificity for detecting PD and subtypes of PD. We found no strong associations between selected patient characteristics and the presence of PD or subtypes of PD.
conclusion59% of patients with SLE have PD, and PD was associated with decreased pulmonary function. Diagnosing PD in SLE remains challenging because clinical assessment and PFTs have limited utility. Accurate diagnosis often requires HRCT or other specialised investigations. TRIAL REGISTRATION NUMBER: NCT06087523.
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