ArticleBMJ open2026
Feasibility and effectiveness of a multicomponent and multilevel personalised lifestyle intervention for adults with intellectual disabilities: protocol for a feasibility and multiple baseline one-arm effectiveness study.
Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe LIFE-ID (lifestyle interventions for adults with intellectual disabilities) intervention, a multicomponent and multilevel lifestyle programme, was developed to improve the lifestyle of adults with ID and the support provided by their interpersonal and organisational environment. This paper describes the protocol of a multiple baseline one-arm feasibility and effectiveness study of the LIFE-ID intervention. METHOD AND ANALYSIS: To evaluate the effectiveness of the LIFE-ID intervention for adults with ID, alongside an embedded assessment of feasibility, we employ a one-arm multiple-baseline trial in the Netherlands, in collaboration with healthcare organisations providing support to adults with ID. The LIFE-ID intervention intervenes at intrapersonal, interpersonal and organisational levels and uses a tailored approach to improve both physical activity and dietary quality in adults with ID. To support healthcare professionals in selecting interventions, the lifestyle support tool was developed, including existing, effective, and ID-specific nutrition and physical activity interventions. The lifestyle support tool takes into account intrapersonal, interpersonal and organisational characteristics and considers the participants' wishes and needs related to their personal lifestyle goals. An embedded feasibility evaluation of the LIFE-ID intervention is conducted with the first 15 participants in the study and their involved healthcare professionals. Information on dose delivered, dose received, acceptability and fidelity of the intervention performance compared with the description is retrieved through biweekly reflection forms obtained from direct support professionals. Group interviews are conducted to collect feedback on the experiences with the LIFE-ID intervention discussing the following topics: acceptance and suitability of the intervention, and barriers and facilitators during execution. Outcomes related to the lifestyle support tool include usability, usefulness and ease of use. To evaluate the effectiveness of the 6-month LIFE-ID intervention, 80 adults (≥18 years) with ID are included (including 15 participants from the feasibility evaluation). The primary outcome is physical activity. Secondary outcomes on the intrapersonal level include dietary quality, physical fitness, body composition, calf circumference, blood pressure, heart rate, frailty, anxiety, depression, behavioural problems and goal attainment. On the interpersonal level, outcomes include attitude of professionals towards support in healthy exercise and nutrition. On the organisational level, outcomes are barriers and facilitators associated with creating a healthy living environment, and determinants that affect the implementation of the LIFE-ID intervention. ETHICS AND DISSEMINATION: The study protocol is approved by the Medical Ethics Review Board of the University Medical Center Groningen (METc 2023-520). Written consent is obtained from all participants who are capable to provide consent, and from legal representatives when they are not. Study findings will be disseminated through peer-reviewed publications, conference presentations and accessible summaries for participants, families and healthcare organisations. TRIAL REGISTRATION NUMBER: The study has been registered in the Overview of Medical Research in the Netherlands (OMON; NL85438), which is linked to the International Clinical Trial Registry Platform (ICTRP).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.