ArticlePoultry science2026
Enhanced endocrine-metabolic support and axonemal assembly in high-sperm-motility geese: insights from testicular cellular heterogeneity by scRNA-seq.
Article in Poultry science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Sperm motility is a key determinant of male fertility and is regulated by coordinated interactions within the spermatogenic niche. To investigate the basis of sperm motility divergence in geese, 60 ganders with sperm motility values within the physiological range were ranked, and the top and bottom 10% were assigned to high-sperm-motility (H) and low-sperm-motility (L) cohorts (n = 6). Semen characteristics, testicular histology, and plasma endocrine, antioxidant, and metabolic indices were compared between cohorts, and for single-cell RNA sequencing, three ganders were selected from each cohort to form the H and L groups for testicular analysis. Compared with the L cohort, the H cohort showed significantly higher sperm motility, semen volume, testis weight, testicular parenchyma area, seminiferous epithelium thickness, seminiferous tubule diameter, and plasma levels of testosterone, luteinizing hormone, total antioxidant capacity, superoxide dismutase, catalase, albumin, and high-density lipoprotein cholesterol, but significantly lower testicular interstitium area, and plasma levels of prolactin, corticosterone, malondialdehyde, H
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