Evidence map›Paper›PMID 41915653›Full record

ArticlePloS one2026

Developing a programme theory of a complex, home-based rehabilitation intervention for recovery after an episode of delirium.

Shruti Raghuraman, Sarah Morgan-Trimmer, Rob Anderson, Victoria A Goodwin, Linda Clare, Ellen Richards, Alison Bingham, Elizabeth Goodwin, Rowan Harwood, Annie Hawton and 5 more

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Shruti RaghuramanFaculty of Health and Life Sciences, Department of Health and Community Sciences, University of Exeter, Exeter, United Kingdom.ORCID https://orcid.org/0000-0002-7366-1147
Sarah Morgan-TrimmerSchool of Primary Care, Population Sciences and Medical Education, University of Southampton, Southampton, United Kingdom.
Rob AndersonFaculty of Health and Life Sciences, Department of Health and Community Sciences, University of Exeter, Exeter, United Kingdom.
Victoria A GoodwinFaculty of Health and Life Sciences, Department of Health and Community Sciences, University of Exeter, Exeter, United Kingdom.
Linda ClareFaculty of Health and Life Sciences, Department of Health and Community Sciences, University of Exeter, Exeter, United Kingdom.ORCID https://orcid.org/0000-0003-3989-5318
Ellen RichardsRoyal Devon University Healthcare NHS Trust, Exeter, United Kingdom.
Alison BinghamFaculty of Health and Life Sciences, Department of Health and Community Sciences, University of Exeter, Exeter, United Kingdom.
Elizabeth GoodwinHealth Economics Group, University of Exeter Medical School, University of Exeter, Exeter, United Kingdom.ORCID https://orcid.org/0000-0003-1351-9170
Rowan HarwoodSchool of Health Sciences, University of Nottingham, Queens Medical Centre, Nottingham, United Kingdom.ORCID https://orcid.org/0000-0002-4920-6718
Annie HawtonHealth Economics Group, University of Exeter Medical School, University of Exeter, Exeter, United Kingdom.
Aseel MahmoudFaculty of Health and Life Sciences, Department of Health and Community Sciences, University of Exeter, Exeter, United Kingdom.ORCID https://orcid.org/0000-0001-6332-8239
Sarah Joanna RichardsonAGE Research Group, NIHR Newcastle Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Foundation Trust, Cumbria Northumberland Tyne and Wear NHS Foundation Trust and Faculty of Medical Sciences Newcastle University, Newcastle upon Tyne, United Kingdom.
Jinpil UmFaculty of Health and Life Sciences, Department of Health and Community Sciences, University of Exeter, Exeter, United Kingdom.ORCID https://orcid.org/0000-0002-6314-0508
Obioha C UkoumunneNIHR Applied Research Collaboration South West Peninsula, University of Exeter, Exeter, United Kingdom.
Louise AllanFaculty of Health and Life Sciences, Department of Health and Community Sciences, University of Exeter, Exeter, United Kingdom.ORCID https://orcid.org/0000-0002-8912-4901

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDelirium in older adults is associated with persistent cognitive and functional decline, increased institutionalisation, and higher mortality. Evidence-based strategies to support recovery after hospitalisation remain limited. This paper outlines the development and refinement of the programme theory underpinning RecoverED, a novel, home-based, multicomponent rehabilitation intervention designed to support post-delirium recovery.

methodsWe applied a realist-informed, multi-stage process to develop the RecoverED programme theory. This included a rapid realist review, qualitative interviews with older adults, carers, and healthcare professionals, an expert panel workshop, iterative programme theory meetings, and a process evaluation embedded within a single-arm feasibility trial. Data were synthesised into a logic model linking intervention components to hypothesised mechanisms and outcomes.

resultsThe programme theory outlines how cognitive and physical rehabilitation, psychosocial support, health monitoring, lifestyle guidance, and delirium education are expected to promote recovery. Cognitive activities aim to rebuild executive function and daily independence; physical rehabilitation maintains mobility; psychosocial support reduces anxiety and promotes confidence; health monitoring and lifestyle guidance address comorbidities; and delirium education supports sense-making. Key mechanisms include personalised goal-setting, continuity of professional support, and integration with community services. The process evaluation within the feasibility trial confirmed the relevance and acceptability of these pathways, while suggesting refinements to training, psychosocial strategies, and education delivery.

conclusionThis paper provides an empirically grounded framework detailing the development and refinement of a programme theory for post-delirium rehabilitation, illustrating the value of flexible, theory-driven approaches to guiding recovery.

Indexed as

DeliriumHome Care ServicesAgedAged, 80 and overFemaleHumansMale

Identifiers

PMID41915653
PMCPMC13038012

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.