Evidence map›Paper›PMID 41915201›Full record

ReviewHNO2026

[Prevention in oncological follow-up].

Matthias Santer, Charles Schmit, Lukas Schmutzler, Daniel Dejaco, Benedikt Hofauer

Abstract readEnglish AbstractReview
In one paragraph

Review in HNO, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Matthias SanterUniversitätsklinik für Hals‑, Nasen‑, Ohrenheilkunde, Medizinische Universität Innsbruck, Anichstr. 35, 6020, Innsbruck, Österreich.
Charles SchmitUniversitätsklinik für Hals‑, Nasen‑, Ohrenheilkunde, Medizinische Universität Innsbruck, Anichstr. 35, 6020, Innsbruck, Österreich. charles.schmit@tirol-kliniken.at.
Lukas SchmutzlerUniversitätsklinik für Hals‑, Nasen‑, Ohrenheilkunde, Medizinische Universität Innsbruck, Anichstr. 35, 6020, Innsbruck, Österreich.
Daniel DejacoUniversitätsklinik für Hals‑, Nasen‑, Ohrenheilkunde, Medizinische Universität Innsbruck, Anichstr. 35, 6020, Innsbruck, Österreich.
Benedikt HofauerUniversitätsklinik für Hals‑, Nasen‑, Ohrenheilkunde, Medizinische Universität Innsbruck, Anichstr. 35, 6020, Innsbruck, Österreich.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn light of increasing remission and 5‑year survival rates, prevention-orientated follow-up care of patients after head and neck cancer is becoming increasingly relevant. In addition to oncologic surveillance, measures aimed at preventing recurrent, second primaries, and long-term functional sequalae are gaining importance.

objectiveThe aim of this review is to analyze preventive strategies in the follow-up care of patients with head and neck cancer. MATERIALS AND

methodsA narrative literature review was conducted in PubMed, focusing on prevention-oriented follow-up care in head and neck cancer. In addition, national and international guidelines (Association of the Scientific Medical Societies in Germany, AWMF; National Comprehensive Cancer Network, NCCN) were considered.

resultsStructured follow-up programs enable early detection of local recurrences and treatment-associated secondary neoplasms. Molecular approaches such as liquid biopsy offer promising perspectives for individualized, risk-adapted follow-up care but require further prospective validation. Lifestyle interventions, particularly smoking and alcohol cessation, are associated with a reduction in the risk of recurrence and second primary tumors. Human papillomavirus (HPV) vaccination exerts a preventive effect within the framework of primary prevention of HPV-associated tumors. Early functional rehabilitation in the domains of voice, swallowing, nutrition, and mobility substantially contributes to the prevention of persistent functional deficits.

conclusionStructured interdisciplinary follow-up care enables early detection of recurrence and improves functional outcomes as well as quality of life. However, innovative approaches require further clinical validation.

Indexed as

AftercareHead and Neck NeoplasmsNeoplasm Recurrence, LocalHumansNeoplasms, Second PrimaryDisease managementHead and neck neoplasmsPreventionSquamous cell carcinomaTreatment outcome

Identifiers

PMID41915201
PMCPMC13109146

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.