ReviewArchives of toxicology2026
Effects of micro- and nano-plastics exposure on cellular senescence: an overview.
Review in Archives of toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Micro- and nano-plastics (MNPs) contamination has recently become a widespread concern. These particles have been detected in multiple human organs. MNPs can enter the human body through three ways: diet intake, inhalation and skin contact, subsequently entering the bloodstream and distributing throughout the body's tissue systems. The health risks posed by MNPs exposure are believed to be linked to cellular senescence, a state of stable cell growth arrest that significantly increases the risk of age-related diseases. The mechanisms of MNPs-induced cellular senescence are primarily associated with oxidative stress and DNA damage, and involve signaling pathways such as eNOS/SIRT1, cGAS-STING, and NF-κB. In this review, we examine the exposure pathways and distribution of MNPs in the human body, the characteristics and mechanisms of MNPs-induced cellular senescence, and potential therapeutic interventions to counteract these effects. We aim to provide state-of-the-art information on the mechanism of MNPs-induced cellular senescence and preventive and curative measures, thereby stimulating future research to minimize the health hazards of their exposure.
Indexed as
Identifiers
41915189What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.