Evidence map›Paper›PMID 41915188›Full record

ArticleArchives of toxicology2026

Mechanism-based inactivation of CYP2D6 by imperatorin and drug-drug interaction in vitro and in vivo.

Hualu Wu, Lu Cao, Peiqi Wang, Ruibin Li, Jun Wu, Haoxin Fu, Yan Chen, Shiqi Jiang, Ren-Ai Xu

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hualu WuThe First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.ORCID http://orcid.org/0009-0005-5976-5352
Lu CaoThe First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Peiqi WangThe First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Ruibin LiThe First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Jun WuThe First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Haoxin FuThe First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Yan ChenThe First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Shiqi JiangThe First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Ren-Ai XuThe First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China. xra@wmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CYP2D6CYP3A4HeracleninImperatorinMechanism-based inactivation

Identifiers

PMID41915188

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.