ArticleJapanese journal of radiology2026
Non-contrast MRI features of mucin plugs and mural nodules in pancreatic cystic lesions.
Article in Japanese journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeNon-contrast MRI characteristics can help differentiate mucin plugs from mural nodules in pancreatic cystic lesions. To identify MRI features that differentiate non-enhancing lesions from true mural nodules in pancreatic cystic lesions. MATERIALS AND
methodsWe retrospectively evaluated 90 patients with pancreatic cystic lesions containing 101 nodular components (62 non-enhancing, 22 benign enhancing, 17 high-risk). Two experienced radiologists independently assessed multiple non-contrast MRI characteristics, including signal-intensity patterns, shape, and their cyst-wall relationship. The reference standard was the contrast-enhanced pattern, with histopathology for resected specimens or minimum 2-year stability for presumed mucin plugs. Diagnostic performance was evaluated in binary logistic regression models.
resultsOnly the non-enhancing lesions (41.9%) showed the "target sign" (layered appearance due to different central- and peripheral-portion signal intensities), providing 100% specificity for identifying non-enhancing lesions. The non-enhancing lesions were predominantly oval-shaped (93.5%) with posterior-wall attachment (85.5%), whereas enhancing lesions showed a complex morphology. On diffusion-weighted imaging (DWI), 93.5% of the non-enhancing lesions showed low signal intensity and 95.2% showed high apparent diffusion coefficient (ADC) values, contrasting with high DWI signal (82.4%) and low ADC values (82.4%) in the high-risk lesions. A multiparameter model achieved excellent diagnostic performance with an area under the curve of 0.97 for differentiating non-enhancing from enhancing lesions and 0.92 for distinguishing non- or benign enhancing from high-risk lesions.
conclusionsNon-contrast MRI features, particularly the target sign, shape characteristics, and cyst-wall relationship can reliably differentiate mucin plugs from true mural nodules in pancreatic cystic lesions, potentially reducing unnecessary invasive procedures.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.