Evidence map›Paper›PMID 41915100›Full record

ArticleJapanese journal of ophthalmology2026

Longitudinal changes in retinal nerve fiber layer thickness after vitrectomy for vitreomacular traction syndrome.

Gee-Hyun Kim, Young-Geun Park, Young-Hoon Park

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Article in Japanese journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Gee-Hyun KimDepartment of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul, 06591, Republic of Korea.
Young-Geun ParkDepartment of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul, 06591, Republic of Korea.
Young-Hoon ParkDepartment of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul, 06591, Republic of Korea. parkyh@catholic.ac.kr.ORCID http://orcid.org/0000-0001-9553-3069

Funding

National Research Foundation of Korea RS-2023-00253065
6 · The paper itself

Abstract

purposeTo investigate long-term changes in peripapillary retinal nerve fiber layer thickness (RNFLT) after surgery for vitreomacular traction syndrome (VMTS), and to identify prognostic factors for surgical outcomes. STUDY

designRetrospective chart review.

methodsThis retrospective study included 34 eyes from 34 patients with unilateral VMTS who underwent pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling and completed a 12-month follow-up. Best-corrected visual acuity (BCVA), central macular thickness (CMT), and peripapillary RNFLT were measured at baseline and at 1, 3, 6, and 12 months postoperatively using swept-source optical coherence tomography (OCT). Longitudinal changes and baseline predictors of visual outcomes were analyzed.

resultsBCVA improved significantly from 3 months postoperatively (P < 0.001), while CMT reduction was evident from 1 month (P < 0.001). RNFLT progressively decreased across all quadrants, with early thinning in the inferior sector (P = 0.014). Compared with fellow eyes, operated eyes showed greater temporal RNFLT preoperatively but thinner global and inferior RNFLT at 12 months. Better postoperative BCVA correlated with better baseline BCVA, thinner preoperative CMT, and thicker preoperative inferior RNFLT, although baseline BCVA was the strongest independent predictor.

conclusionsVMTS eyes demonstrated progressive RNFLT thinning after surgery, reflecting both resolution of vitreous traction and underlying neuronal vulnerability. Baseline BCVA was the most reliable prognostic factor, while CMT and inferior RNFLT may provide additional insights into surgical outcomes.

Indexed as

Nerve FibersRetinal DiseasesRetinal Ganglion CellsTomography, Optical CoherenceVisual AcuityVitrectomyVitreous BodyVitreous DetachmentAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPostoperative PeriodRetrospective StudiesInternal limiting membraneOptical coherence tomographyRetinal nerve fiber layerVitrectomyVitreomacular traction syndrome

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.