ArticleJapanese journal of ophthalmology2026
Establishing absolute and vitreous-normalized reference apparent diffusion coefficient values of the lacrimal gland in healthy individuals.
Article in Japanese journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo establish normative apparent diffusion coefficient (ADC) values of the lacrimal gland in a large cohort of healthy subjects and to compare the results with previously reported data. STUDY
designRetrospective cohort study.
methodsBrain magnetic resonance (MR) images of 260 healthy individuals were retrospectively analyzed. ADC measurements were performed bilaterally using a standardized region of interest (ROI) technique. The values were compared according to age and sex. To ensure normalization and standardization, vitreous ADC measurements were performed using the same ROI used for lacrimal gland measurements. Lacrimal gland ADC values were divided by vitreous ADC values.
resultsThe lacrimal gland ADCmean value was 1.29 ± 0.14 ×10⁻
conclusionThis study presents a large series on normative ADC values of the lacrimal gland in healthy individuals. The results provide reliable reference data that may assist in the differential diagnosis of inflammatory and neoplastic pathologies.
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