Trial reportClinical oral investigations2026
Preventive exercise intervention for trismus in head and neck cancer - a randomized study : Preventive exercise intervention for trismus.
Trial report in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
objectivesThe aim of the study was to investigate the effect of preventive exercise therapy on radiation-induced trismus in head and neck cancer. MATERIALS AND
methodsEighty-nine patients (n = 89) with newly diagnosed head and neck cancer were included and randomized to either the preventive exercise intervention group (n = 45) or the control group. (n = 44). The intervention group was instructed to perform jaw opening exercises once daily.
resultsNo differences were found in mouth opening capacity between the intervention and the control groups in the first year after oncological treatment. At the 6-month follow-up, the prevalence of trismus was 7% and 19% in the intervention and the control groups, respectively, and at the 12-month follow-up, 7% and 3%, respectively; these differences were not statistically significant.
conclusionPreventive exercise was not effective in improving trismus and mouth opening-related outcomes in this randomized study. A surprisingly low prevalence of trismus was seen in both groups in the first year after radiotherapy. CLINICAL RELEVANCE: There is reason to believe that newer radiotherapy regimens have reduced radiation trismus in HNC. Although prophylactic intervention does not appear to influence mouth opening capacity, it is important to carefully monitor mouth opening in patients undergoing radiotherapy for HNC. Early detection of a reduction in MIO can permit early initiation of exercise interventions for trismus.
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