Evidence map›Paper›PMID 41914743›Full record

ArticlemSystems2026

Human milk bacteria assembled into functionally distinct synthetic communities in infant formula differently affect intestinal physiology and microbiota in neonatal mini-piglets.

Charles Le Bras, Gwenaelle Randuineau, Armelle Cahu, Patrice Dahirel, Sylvie Guérin, Regis Janvier, Véronique Romé, Lucie Rault, Marie-Bernadette Maillard, Amandine Bellanger and 4 more

Abstract read
In one paragraph

Article in mSystems, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A synthetic bacterial community made of human milk isolated strains is an effective strategy to prevent food allergy in a mouse model.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Charles Le BrasInstitut NuMeCan, INRAE, INSERM, Université de Rennes, Saint Gilles, France.
Gwenaelle RanduineauInstitut NuMeCan, INRAE, INSERM, Université de Rennes, Saint Gilles, France.
Armelle CahuInstitut NuMeCan, INRAE, INSERM, Université de Rennes, Saint Gilles, France.
Patrice DahirelInstitut NuMeCan, INRAE, INSERM, Université de Rennes, Saint Gilles, France.
Sylvie GuérinInstitut NuMeCan, INRAE, INSERM, Université de Rennes, Saint Gilles, France.
Regis JanvierInstitut NuMeCan, INRAE, INSERM, Université de Rennes, Saint Gilles, France.
Véronique RoméInstitut NuMeCan, INRAE, INSERM, Université de Rennes, Saint Gilles, France.
Lucie RaultSTLO, INRAE, Institut Agro Rennes Angers, Rennes, France.
Marie-Bernadette MaillardSTLO, INRAE, Institut Agro Rennes Angers, Rennes, France.
Amandine BellangerPediatric Department, CHU Rennes, CIC-Inserm 1414, Rennes, France.
Yves Le LoirSTLO, INRAE, Institut Agro Rennes Angers, Rennes, France.
Sophie BlatInstitut NuMeCan, INRAE, INSERM, Université de Rennes, Saint Gilles, France.
Sergine Even *STLO, INRAE, Institut Agro Rennes Angers, Rennes, France.
Isabelle Le Huërou-Luron *Institut NuMeCan, INRAE, INSERM, Université de Rennes, Saint Gilles, France.ORCID 0000-0002-1769-5246

Funding

Bretagne Biotechnologie Alimentaire (BBA) Milk Valley association Prolific projectConseil Régional de Bretagne no. 19008213Conseil Régional des Pays de la Loire no. 2019-013227
6 · The paper itself

Abstract

The contribution of human milk (HM) microbiota to infant gut health was addressed by evaluating the impact of HM bacteria, combined in two synthetic communities (SynComs) exhibiting anti-inflammatory (AI) or high immunomodulatory (HI) properties

Indexed as

BacteriaGastrointestinal MicrobiomeInfant FormulaIntestinesMilk, HumanAnimalsAnimals, NewbornFecesHumansSwineSwine, Miniaturegut barriergut microbiotagut physiologyhuman microbiotahuman milkimmunityinfant nutrition

Identifiers

PMID41914743
PMCPMC13098267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.