Evidence map›Paper›PMID 41914736›Full record

ReviewmSystems2026

Heterogeneity of bacterial host-pathogen interactions across biological scales.

Juan Alfonso Redondo, Niharika Purkait, Pawel Paszek

Abstract readReview
In one paragraph

Review in mSystems, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Juan Alfonso RedondoInstitute of Fundamental Technological Research, Polish Academy of Sciences, Warsaw, Poland.ORCID 0000-0002-9280-9848
Niharika PurkaitInstitute of Fundamental Technological Research, Polish Academy of Sciences, Warsaw, Poland.ORCID 0009-0007-3780-2866
Pawel PaszekInstitute of Fundamental Technological Research, Polish Academy of Sciences, Warsaw, Poland.ORCID 0000-0002-0363-0716

Funding

Narodowa Agencja Wymiany Akademickiej BPN/PPO/2022/1/00002Narodowe Centrum Nauki 2022/45/B/NZ6/01643
6 · The paper itself

Abstract

Recent advances in single-cell technologies have revealed the dynamic and heterogeneous nature of host-pathogen interactions at the single-cell level. This review explores how cellular variability-both within clonal bacterial populations and among genetically identical host cells-gives rise to distinct infection outcomes, from pathogen clearance to persistence across multiple biological scales, from single cells to tissues and the whole organism. We highlight the conceptual and technological progress that has enabled the dissection of these interactions at single-cell resolution, including microscopy, single-cell transcriptomics, proteomics, and emerging dual RNA-seq and spatial approaches. Drawing on examples from well-characterized bacterial pathogens like

Indexed as

BacteriaBacterial InfectionsHost-Pathogen InteractionsAnimalsHumansListeria monocytogenesMycobacterium tuberculosisProteomicsSingle-Cell AnalysisSingle-Cell Gene Expression Analysiscellular heterogeneityhost-pathogen interactionsinfection biologyListeria monocytogenesMycobacterium tuberculosisSalmonella entericasingle-cell biology

Identifiers

PMID41914736
PMCPMC13098198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.