Evidence map›Paper›PMID 41914659›Full record

ArticleACS infectious diseases2026

Modulating Micrococcal Nuclease-Triggered Antibiotic Releases for One-Stage Revisions of

Jordan D Skelly, Feiyang Chen, Jie Song

Abstract read
In one paragraph

Article in ACS infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jordan D SkellyDepartment of Orthopedics and Physical Rehabilitation, UMass Chan Medical School, Worcester, Massachusetts 01655, United States.ORCID 0000-0002-1310-6555
Feiyang ChenDepartment of Orthopedics and Physical Rehabilitation, UMass Chan Medical School, Worcester, Massachusetts 01655, United States.
Jie SongDepartment of Orthopedics and Physical Rehabilitation, UMass Chan Medical School, Worcester, Massachusetts 01655, United States.ORCID 0000-0001-7554-5564

Funding

Synergistic anti-fouling coating and minimal systemic antibiotic injections for combating periprosthetic infectionsR01AR080431 · NIAMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Jie Song · 2022 to 2026
$2.8M
Micrococcal nuclease-triggered antibiotics release: a prophylactic implant coating against S. aureus infectionsR01AR078044 · NIAMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SONG, JIE · 2020 to 2024
$2.4M
Scanning Electron Microscope for Core EM FacilityS10RR021043 · NCRR · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI CRAIG, ROGER W · 2007 to 2007
$498k
Request for VivaCT 75 High Speed in vivo MicroCT ScannerS10RR027082 · NCRR · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SONG, JIE · 2010 to 2010
$441k
NCRR NIH HHS S10 RR021043NCRR NIH HHS S10 RR027082NIAMS NIH HHS R01 AR078044NIAMS NIH HHS R01 AR080431
6 · The paper itself

Abstract

Periprosthetic joint infections caused by

Indexed as

Anti-Bacterial AgentsMicrococcal NucleaseProsthesis-Related InfectionsStaphylococcal InfectionsStaphylococcus aureusAmpicillinAnimalsRatsVancomycinAmpicillinAnti-Bacterial AgentsMicrococcal NucleaseVancomycin1-stage revisionampicillinhydrogel coatingmicrococcal nucleaseon-demand releaseperiprosthetic infectionStaphylococcus aureusvancomycin

Identifiers

PMID41914659
PMCPMC13089311

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.