Evidence map›Paper›PMID 41914638›Full record

Trial reportAntimicrobial agents and chemotherapy2026

Adjunctive povidone-iodine for

Revathi Rajaraman, Isabell Kassaye, Sankalp S Sharma, N Venkatesh Prajna, Prajna Lalitha, Arunkumar Panigrahi, Ram Rammohan, Krisianne M Aromin, Catherine Cook, Travis C Porco and 3 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Revathi Rajaraman *Cornea Department, Aravind Eye Hospital, Coimbatore, India.
Isabell Kassaye *Francis I Proctor Foundation, University of California, San Francisco, California, USA.
Sankalp S SharmaDepartment of Cornea and Refractive Surgery, Aravind Eye Hospital, Madurai, India.
N Venkatesh PrajnaDepartment of Cornea and Refractive Surgery, Aravind Eye Hospital, Madurai, India.
Prajna LalithaDepartment of Microbiology, Aravind Eye Hospital, Madurai, India.
Arunkumar PanigrahiDepartment of Cornea and Refractive Surgery, Aravind Eye Hospital, Madurai, India.
Ram RammohanDepartment of Microbiology, Aravind Eye Hospital, Coimbatore, India.
Krisianne M ArominFrancis I Proctor Foundation, University of California, San Francisco, California, USA.
Catherine CookFrancis I Proctor Foundation, University of California, San Francisco, California, USA.
Travis C PorcoFrancis I Proctor Foundation, University of California, San Francisco, California, USA.ORCID 0000-0001-8813-3171
Thomas M LietmanFrancis I Proctor Foundation, University of California, San Francisco, California, USA.ORCID 0000-0001-8216-0240
Gerami D SeitzmanFrancis I Proctor Foundation, University of California, San Francisco, California, USA.
Jeremy D KeenanFrancis I Proctor Foundation, University of California, San Francisco, California, USA.ORCID 0000-0002-7118-1457

Funding

All May See FoundationNEI NIH HHS UG1EY033284, R34EY022368Peierls FoundationResearch to Prevent Blindness
6 · The paper itself

Abstract

The aim of this study was to determine the antiamoebic efficacy of povidone-iodine when used as an adjunct to topical biguanide therapy for

Indexed as

AcanthamoebaAcanthamoeba KeratitisAnti-Infective Agents, LocalPovidone-IodineAdultBiguanidesChlorhexidineFemaleHumansMaleMiddle AgedAnti-Infective Agents, LocalBiguanidesChlorhexidinePovidone-IodineAcanthamoeba keratitismicrobiological techniquespovidone-iodine

Identifiers

PMID41914638
PMCPMC13148041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.