Evidence map›Paper›PMID 41914611›Full record

ArticleJournal of agricultural and food chemistry2026

Vitamin C Alleviates BPA Embryotoxicity by Attenuating Oxidative Stress and DNA Damage-Mediated Apoptosis via Modulation of the ATM/Chk2/p53 Pathway.

Fei Ren, Zhen Lu, Xueping Cheng, Shitong Hao, Lingli Chen, Zhihong Yin, Dongfang Hu, Hongmei Ning, Yaming Ge, Junping He and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of agricultural and food chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fei RenCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang 453003, Henan, China.
Zhen LuCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang 453003, Henan, China.
Xueping ChengCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang 453003, Henan, China.
Shitong HaoCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang 453003, Henan, China.
Lingli ChenCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang 453003, Henan, China.
Zhihong YinCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang 453003, Henan, China.
Dongfang HuCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang 453003, Henan, China.
Hongmei NingCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang 453003, Henan, China.ORCID 0000-0002-9062-0232
Yaming GeCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang 453003, Henan, China.
Junping HeCollege of Veterinary Medicine, Shanxi Agricultural University Jinzhong 030801, Shanxi, China.ORCID 0000-0002-5069-8385
Shanshan ShenCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang 453003, Henan, China.ORCID 0009-0007-1101-2698
Wei ZhangCollege of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang 453003, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bisphenol A (BPA), an environmental contaminant that migrates from food packaging, poses significant risks to embryonic development. This study investigated the protective effects and mechanisms of vitamin C (l-ascorbic acid) against BPA-induced embryotoxicity using

Indexed as

ApoptosisAscorbic AcidAtaxia Telangiectasia Mutated ProteinsBenzhydryl CompoundsCheckpoint Kinase 2DNA DamageOxidative StressPhenolsTumor Suppressor Protein p53Xenopus laevisAnimalsBisphenol A CompoundsEmbryonic DevelopmentEmbryo, NonmammalianMiceReactive Oxygen SpeciesAscorbic AcidAtaxia Telangiectasia Mutated ProteinsBenzhydryl Compoundsbisphenol ABisphenol A CompoundsCheckpoint Kinase 2PhenolsReactive Oxygen SpeciesTumor Suppressor Protein p53apoptosisbisphenol ADNA damageembryotoxicityoxidative stressvitamin C

Identifiers

PMID41914611
PMCPMC13088246

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.