Evidence map›Paper›PMID 41914436›Full record

Trial reportClinical and experimental dental research2026

Comparison of Post-Cementation Sensitivity Between Resin Modified Glass Ionomer Cement and Conventional Glass Ionomer Cement as a Luting Material-A Randomized Clinical Trial.

Shamsul Alam, Naveed Sadiq, Hend Mohamed Elsayed, Sheema Shakir, Nasser Hussein Shaheen, Ahmed Mohammed Elmarakby, Asif Rehman

Registry-linked trialAbstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Clinical and experimental dental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07102121 (Comparison of Post Cementation Sensitivity Between Resin-Modified Glass Ionomer Cement and Conventional Glass Ionomer Cement as a Luting Material), which is not on this map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07102121 naenrolling by invitationnot on this map

Comparison of Post Cementation Sensitivity Between Resin-Modified Glass Ionomer Cement and Conventional Glass Ionomer Cement as a Luting Material: A Randomized Clinical Trial

TypeinterventionalSponsorSaidu College of DentistryRan2025 to 2025Enrolled496ConditionsDental Pulp Disease, Dental Pain and Sensation DisorderArmsluting material applaication with Modified Glass Ionomer Cement (RMGIC)
3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Shamsul AlamDepartment of Public Health, Khyber Medical University, Peshawar, Pakistan.ORCID 0000-0001-7410-3852
Naveed SadiqInstitute of Public Health and Social Sciences, Khyber Medical University, Peshawar, Pakistan.ORCID 0000-0002-4141-0714
Hend Mohamed ElsayedRestorative Dentistry, Department of Restorative and Prosthetic Dental Sciences, College of Dentistry, Dar Al Uloom University, Riyadh, Saudi Arabia.ORCID 0009-0008-6816-653X
Sheema ShakirDepartment of Prosthodontics, Khyber College of Dentistry, Peshawar, Pakistan.ORCID 0009-0000-4197-6876
Nasser Hussein ShaheenRestorative and Prosthetic Dental Sciences Department, Dar Al Uloom University, Riyadh, Saudi Arabia.ORCID 0000-0002-2521-5281
Ahmed Mohammed ElmarakbyDepartment of Operative Dentistry, Faculty of Dental Medicine, Al Azhar University, Assiut Branch, Cairo, Egypt.ORCID 0000-0002-9950-5900
Asif RehmanBath Spa University, Bath, UK.ORCID 0000-0002-6133-3349

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare post-cementation sensitivity between resin-modified glass ionomer cement (RMGIC) and conventional glass ionomer cement (GIC) used as luting agents for single crowns. MATERIALS AND

methodsThis randomized controlled trial was conducted at Saidu College of Dentistry, Swat, Pakistan. A total of 496 eligible participants were randomized into two groups: GIC (n = 248) and RMGIC (n = 248). Post-cementation sensitivity was recorded at 24 h, 1 week, and 1 month using a 10-point visual analog scale (VAS), with scores categorized as no, mild, moderate, or severe sensitivity. Data were analyzed using Mann-Whitney U tests, and linear mixed-effects models adjusted for age, gender, jaw, and prosthesis location.

resultsBaseline demographic and clinical characteristics were comparable between groups. Post-cementation sensitivity was consistently lower in the RMGIC group compared to the GIC group across all time points. Median sensitivity scores at 24 h were 4.0 (GIC) versus 3.0 (RMGIC, p < 0.001); at 1 week, 2.0 versus 1.0 (p < 0.001); and at 1 month, both minimal but significantly lower in the RMGIC group (p < 0.001). The adjusted mixed-effects model confirmed that RMGIC significantly reduced sensitivity compared to GIC (β = -0.53; OR 0.59, 95% CI 0.46-0.75; p < 0.001). Sensitivity was highest at 24 h (β = 2.96; OR 19.3, 95% CI 15.3-24.3; p < 0.001), followed by 1 week (β = 0.81; OR 2.25, 95% CI 1.77-2.86; p < 0.001), and declined markedly by 1 month. Age showed a modest protective effect (β = -0.008; OR 0.99, 95% CI 0.99-1.00; p = 0.04), while gender, jaw, and prosthesis location were not significant predictors. A significant interaction at 24 h showed RMGIC provided an additional reduction in sensitivity compared to GIC (β = -0.83; OR 0.44, 95% CI 0.31-0.61; p < 0.001).

conclusionRMGIC demonstrated significantly lower post-cementation sensitivity compared to conventional GIC.

trial registrationThis trial was retrospectively registered with Clinical Trials Registry of ClinicalTrials.gov(registration#NCT07102121) on August 3, 2025.

Indexed as

CementationCrownsDentin SensitivityGlass Ionomer CementsResin CementsAdultFemaleHumansMaleMiddle AgedYoung AdultGlass Ionomer CementsResin Cementsfixed partial denturepost‐cementation sensitivityresin‐modified glass ionomer cement

Identifiers

PMID41914436
PMCPMC13140619

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.