Evidence map›Paper›PMID 41914363›Full record

ArticleJournal of the American Heart Association2026

Patient Care Pathways and Outcomes Following Newly Diagnosed Atrial Fibrillation.

Emily P Zeitler, Larry R Jackson, Andrea Natale, Jonathan P Piccini, Sean D Pokorney, Andrea M Russo, Roopinder K Sandhu, Rahul Khanna, Maximiliano Iglesias, Yiran Rong and 1 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Emily P ZeitlerDartmouth Health Lebanon NH USA.ORCID 0000-0002-4848-4775
Larry R JacksonDuke University Medical Center Durham NC USA.ORCID 0000-0002-0195-1081
Andrea NataleTexas Cardiac Arrhythmia Institute Austin TX USA.ORCID 0000-0002-5487-0728
Jonathan P PicciniDuke University Medical Center Durham NC USA.ORCID 0000-0003-0772-2404
Sean D PokorneyDuke University Medical Center Durham NC USA.ORCID 0000-0002-4345-0816
Andrea M RussoCooper University Hospital Moorestown NJ USA.ORCID 0000-0002-3129-6161
Roopinder K SandhuLibin Cardiovascular Institute University of Calgary Calgary AB Canada.ORCID 0000-0002-2629-3476
Rahul KhannaJohnson & Johnson New Brunswick NJ USA.
Maximiliano IglesiasJohnson & Johnson MedTech Electrophysiology Toronto ON Canada.ORCID 0000-0002-4197-3955
Yiran RongJohnson & Johnson New Brunswick NJ USA.ORCID 0000-0002-8571-3872
T Jared BunchUniversity of Utah School of Medicine Salt Lake City UT USA.ORCID 0000-0001-5349-0136

Funding

Understanding the Influence of Community-level Deprivation and Rural Residence in Cancer CareP20GM148278 · NIGMS · DARTMOUTH-HITCHCOCK CLINIC · PI LAURA Marie PAULIN, Sandra L Wong · 2023 to 2026
$11.6M
NIGMS NIH HHS P20 GM148278
6 · The paper itself

Abstract

backgroundCare pathways for patients with atrial fibrillation (AF) are poorly understood and may influence the likelihood of guideline concordant oral anticoagulation or antiarrhythmic drug therapy and associated outcomes.

methodsAdult patients in the Optum Clinformatics Database (2015-2023) with incident AF were identified. Care pathways, by treating clinician specialty (primary care, cardiology, electrophysiology) during each AF-related visit in the 1 year post diagnosis were examined. Cox regression models were used to assess associations between an electrophysiologist visit and AF-related treatments including antiarrhythmic drug therapy and oral anticoagulation and outcomes including AF-related hospitalizations, heart failure hospitalizations, and stroke.

resultsOf the 37 370 patients included, 7700 (20.6%) had a care pathway including an electrophysiologist visit. Older patients (70-79 and 80+ versus 18-49 years: hazard ratio [HR], 0.71 [95% CI, 0.64-0.78] and HR, 0.57 [95% CI, 0.51-0.63], respectively) and those with a higher CHA

conclusionsCertain demographic groups including older patients had lesser likelihood of electrophysiologist consultation, but guideline concordant care was more likely associated with electrophysiology care pathways. Electrophysiology care pathways were associated with improved outcomes especially among the groups with greatest stroke risk.

Indexed as

Anti-Arrhythmia AgentsAnticoagulantsAtrial FibrillationCritical PathwaysStrokeAdministration, OralAdolescentAdultAgedAged, 80 and overFemaleGuideline AdherenceHospitalizationHumansMaleMiddle AgedAnti-Arrhythmia AgentsAnticoagulantsanticoagulationatrial fibrillationstroke

Identifiers

PMID41914363
PMCPMC13279233

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.