Evidence map›Paper›PMID 41914240›Full record

ArticleBioMed research international2026

Toxicological Assessment of LN20188, a Botanical Combination of Withania somnifera Root and Abelmoschus esculentus Fruit Extracts.

Ravikumar Madireddy, Sundararaju Dodda, Gopichand Chinta, KrishnaRaju Venkata Alluri

Abstract read
In one paragraph

Article in BioMed research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ravikumar MadireddyDepartment of Toxicology, Laila Nutra Private Limited, R&D Centre, Vijayawada, Andhra Pradesh, India.ORCID https://orcid.org/0000-0001-7447-9921
Sundararaju DoddaDepartment of Toxicology, Laila Nutra Private Limited, R&D Centre, Vijayawada, Andhra Pradesh, India.ORCID https://orcid.org/0009-0000-4075-5887
Gopichand ChintaDepartment of Pharmacology & Medical Affairs, Laila Nutra Private Limited, R&D Centre, Vijayawada, Andhra Pradesh, India.ORCID https://orcid.org/0000-0002-1477-773X
KrishnaRaju Venkata AlluriDepartment of Toxicology, Laila Nutra Private Limited, R&D Centre, Vijayawada, Andhra Pradesh, India.ORCID https://orcid.org/0000-0002-0550-7164

Funding

Laila Nutraceuticals LN/20188/18
6 · The paper itself

Abstract

LN20188 is a botanical combination composed of extracts derived from Withania somnifera (L.) Dunal root and Abelmoschus esculentus (L.) Moench fruit. Our earlier investigations revealed the benefits of LN20188 in promoting gut motility and reducing constipation. The current investigation presents the toxicological profile of LN20188 following OECD guidelines for chemical testing. In an acute oral toxicity (AOT) study involving Sprague Dawley rats, no significant signs of toxicity or morbidity were observed, and the lethal dose (LD

Indexed as

AbelmoschusFruitPlant ExtractsPlant RootsWithaniaAnimalsBody WeightFemaleLethal Dose 50MaleMiceNo-Observed-Adverse-Effect LevelOrgan SizeRatsRats, Sprague-DawleyToxicity Tests, AcutePlant ExtractsashwagandhagenotoxicityLN20188no-observed-adverse-effect level (NOAEL)okrasubacute toxicity

Identifiers

PMID41914240
PMCPMC13140333

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.