Evidence map›Paper›PMID 41914155›Full record

ArticleCirculation. Heart failure2026

Effects of Left Atrial Filling Pressure on Exercise Pulmonary Gas Exchange in HFpEF: Does the V-Wave Matter?

Le Huang, Bryce N Balmain, James P MacNamara, Tiffany L Brazile, Michael G Leahy, Christopher M Hearon, Denis J Wakeham, Andrew R Tomlinson, Tony G Babb, Benjamin D Levine and 1 more

Abstract readLetter
In one paragraph

Article in Circulation. Heart failure, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Le HuangUniversity of Texas Southwestern Medical Center, Dallas (L.H., B.N.B., J.P.M.N., T.L.B., M.G.L., C.M.H., D.J.W., A.R.T., T.G.B., B.D.L., S.S.).ORCID 0000-0001-7479-880X
Bryce N BalmainUniversity of Texas Southwestern Medical Center, Dallas (L.H., B.N.B., J.P.M.N., T.L.B., M.G.L., C.M.H., D.J.W., A.R.T., T.G.B., B.D.L., S.S.).ORCID 0000-0002-2642-7083
James P MacNamaraUniversity of Texas Southwestern Medical Center, Dallas (L.H., B.N.B., J.P.M.N., T.L.B., M.G.L., C.M.H., D.J.W., A.R.T., T.G.B., B.D.L., S.S.).ORCID 0000-0003-2795-6021
Tiffany L BrazileUniversity of Texas Southwestern Medical Center, Dallas (L.H., B.N.B., J.P.M.N., T.L.B., M.G.L., C.M.H., D.J.W., A.R.T., T.G.B., B.D.L., S.S.).ORCID 0000-0001-8215-2144
Michael G LeahyUniversity of Texas Southwestern Medical Center, Dallas (L.H., B.N.B., J.P.M.N., T.L.B., M.G.L., C.M.H., D.J.W., A.R.T., T.G.B., B.D.L., S.S.).ORCID 0000-0002-9209-3982
Christopher M HearonUniversity of Texas Southwestern Medical Center, Dallas (L.H., B.N.B., J.P.M.N., T.L.B., M.G.L., C.M.H., D.J.W., A.R.T., T.G.B., B.D.L., S.S.).ORCID 0000-0002-6561-3532
Denis J WakehamUniversity of Texas Southwestern Medical Center, Dallas (L.H., B.N.B., J.P.M.N., T.L.B., M.G.L., C.M.H., D.J.W., A.R.T., T.G.B., B.D.L., S.S.).ORCID 0000-0002-4200-3790
Andrew R TomlinsonUniversity of Texas Southwestern Medical Center, Dallas (L.H., B.N.B., J.P.M.N., T.L.B., M.G.L., C.M.H., D.J.W., A.R.T., T.G.B., B.D.L., S.S.).ORCID 0000-0001-9899-0812
Tony G BabbUniversity of Texas Southwestern Medical Center, Dallas (L.H., B.N.B., J.P.M.N., T.L.B., M.G.L., C.M.H., D.J.W., A.R.T., T.G.B., B.D.L., S.S.).ORCID 0000-0002-0515-2164
Benjamin D LevineUniversity of Texas Southwestern Medical Center, Dallas (L.H., B.N.B., J.P.M.N., T.L.B., M.G.L., C.M.H., D.J.W., A.R.T., T.G.B., B.D.L., S.S.).ORCID 0000-0001-9064-7251
Satyam SarmaUniversity of Texas Southwestern Medical Center, Dallas (L.H., B.N.B., J.P.M.N., T.L.B., M.G.L., C.M.H., D.J.W., A.R.T., T.G.B., B.D.L., S.S.).ORCID 0000-0002-0628-4919

Funding

Targeting skeletal muscle to improve exercise capacity in heart failure with preserved ejection fraction.P01HL137630 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI BABB, TONY G · 2019 to 2023
$11.4M
UT Southwestern NORCP30DK127984 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI Jeffrey M Zigman · 2022 to 2026
$7.4M
NHLBI NIH HHS P01 HL137630NIDDK NIH HHS P30 DK127984
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

exerciseheart failurehemodynamics

Identifiers

PMID41914155
PMCPMC13051774

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.