Evidence map›Paper›PMID 41913950›Full record

ArticleG3 (Bethesda, Md.)2026

Autoregulation of three yeast ribosomal protein genes by splicing inhibition.

David Granas, Anirudh Kesanapally, Michael A White, Gary D Stormo

Abstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

David GranasDepartment of Genetics and Center for Genomics and Systems Biology, Washington University in St Louis School of Medicine, St Louis, MO 63110  United States.
Anirudh KesanapallyDepartment of Genetics and Center for Genomics and Systems Biology, Washington University in St Louis School of Medicine, St Louis, MO 63110  United States.
Michael A WhiteDepartment of Genetics and Center for Genomics and Systems Biology, Washington University in St Louis School of Medicine, St Louis, MO 63110  United States.
Gary D StormoDepartment of Genetics and Center for Genomics and Systems Biology, Washington University in St Louis School of Medicine, St Louis, MO 63110  United States.ORCID 0000-0001-6896-1850

Funding

Single cell tagging of localized RNA from whole populationsR01GM140013 · NIGMS · WASHINGTON UNIVERSITY · PI WHITE, MICHAEL AARON · 2020 to 2022
$1.0M
NIGMS NIH HHS R01 GM140013
6 · The paper itself

Abstract

Yeast ribosomal protein genes RPL18B, RPL28, and RPS22B are autoregulated by inhibition of splicing. This is demonstrated by inserting their introns into a chromosomal copy of GFP and observing repression upon induction of the cognate protein. In RPL18B and RPS22B, a predicted conserved secondary structure within the intron is required for regulation, while in RPL28, it is not.

Indexed as

Gene Expression Regulation, FungalHomeostasisRibosomal ProteinsRNA SplicingSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsIntronsRNA, MessengerRibosomal ProteinsRNA, MessengerSaccharomyces cerevisiae ProteinsautoregulationmRNA structuresplicing

Identifiers

PMID41913950
PMCPMC13232506

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.