Evidence map›Paper›PMID 41913852›Full record

ArticleCureus2026

A Massive Cavernous Mediastinal Haemangioma Causing Superior Vena Cava Obstruction and Extending to the Supraclavicular Space: A Case Report.

Antonios Charokopos, Andreas Granitsas, Georgios T Stathopoulos, Irene Zarvou, Stella Petrou, Pinelopi Anagnostopoulou, Nikos Chondros, Elena Theofanous, Konstantinos Markakis, Tonia Adamides

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Antonios CharokoposSchool of Medicine, University of Cyprus, Nicosia, CYP.
Andreas GranitsasDepartment of Pulmonology, Nicosia General Hospital, Nicosia, CYP.
Georgios T StathopoulosSchool of Medicine, University of Cyprus, Nicosia, CYP.
Irene ZarvouDepartment of Pulmonology, Nicosia General Hospital, Nicosia, CYP.
Stella PetrouDepartment of Pulmonology, Nicosia General Hospital, Nicosia, CYP.
Pinelopi AnagnostopoulouSchool of Medicine, University of Cyprus, Nicosia, CYP.
Nikos ChondrosDepartment of Radiology, Nicosia General Hospital, Nicosia, CYP.
Elena TheofanousDepartment of Histopathology, Nicosia General Hospital, Nicosia, CYP.
Konstantinos MarkakisDepartment of Cardiothoracic Surgery, Nicosia General Hospital, Nicosia, CYP.
Tonia AdamidesDepartment of Pulmonology, Nicosia General Hospital, Nicosia, CYP.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mediastinal haemangiomas are exceptionally rare, benign vascular tumours and account for a very small proportion of all mediastinal masses. Their symptomatology ranges from an incidental finding to significant mass-mediated compression of vital thoracic structures. We report a unique case of a massive mediastinal cavernous haemangioma with supraclavicular and axillary extension, which led to central venous obstruction. A 24-year-old man, with a childhood history of a resected supraclavicular cyst, was found to have a symptomatic right-sided heterogeneous mediastinal mass. Computed tomography (CT) angiography identified the hypervascular mass extending from the anterior mediastinum to the supraclavicular fossa, which caused aneurysmal dilatation of the superior vena cava (SVC), with an extensive collateral venous network. Magnetic resonance imaging (MRI) appearance was highly suggestive of a haemangioma, with three interconnecting regions of sizes 7.5 × 6 cm, 9 × 5 cm, and 8.5 × 1.6 cm. The mass was histologically confirmed by transthoracic needle biopsy as a cavernous haemangioma. Due to signs of venous-phase extravasation into the mediastinum and worsening SVC diameter, embolisation was recommended after a comprehensive multidisciplinary meeting. Our radiopathologic case highlights the diagnostic intricacies of differentiating extremely bulky, but benign, haemangiomas from aggressive mediastinal malignancies. Although surgical excision is the gold standard, the involvement of critical structures, like the SVC, necessitates multidisciplinary discussion and consideration of alternative treatment approaches.

Indexed as

haemangiomamediastinal masssuperior vena cava (svc) syndromethoracic radiologyvascular tumour

Identifiers

PMID41913852
PMCPMC13033231

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