Evidence map›Paper›PMID 41913836›Full record

ArticleCureus2026

Melkersson-Rosenthal Syndrome: A Case Treated With Infliximab.

Francisca A Correia, Adriana Costa, Claudemira Pinto, Vanessa Chaves, Jorge Almeida

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Francisca A CorreiaInternal Medicine Department, Unidade Local de Saúde de São João, Porto, PRT.
Adriana CostaInternal Medicine Department, Unidade Local de Saúde de São João, Porto, PRT.
Claudemira PintoInternal Medicine Department, Unidade Local de Saúde de São João, Porto, PRT.
Vanessa ChavesInternal Medicine Department, Unidade Local de Saúde de São João, Porto, PRT.
Jorge AlmeidaInternal Medicine Department, Unidade Local de Saúde de São João, Porto, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melkersson-Rosenthal Syndrome (MRS) is a rare disorder of unknown etiology, clinically characterized by a triad of recurrent orofacial swelling with facial palsy and a fissured tongue. Diagnosis is based on physical findings and history, with a biopsy potentially needed for histological confirmation. We present a case of a 40-year-old woman, referred by her stomatologist to our Department of Internal Medicine for granulomatous cheilitis. After excluding other etiologies and in the presence of a compatible biopsy, the diagnosis of MRS was made. There is no standardized treatment for MRS, and most therapeutic decisions are based on isolated case reports and small case series; management is, therefore, individualized according to patient response. In the current reported case, after several different therapeutic regimens had failed, the patient was treated with infliximab and has been improving progressively thereafter.

Indexed as

diagnosisgranulomatous cheilitisinfliximabmelkersson-rosenthal syndromeorofacial swellingtreatment

Identifiers

PMID41913836
PMCPMC13033241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.