Evidence map›Paper›PMID 41913695›Full record

SynthesisThe Australian & New Zealand journal of obstetrics & gynaecology2026

Asthma Control During Pregnancy and Adverse Perinatal Outcomes: A Systematic Review.

Emilie Johanne Vedtofte Haastrup, Esther Bay Smedegaard, Anne Vejen Hansen, Charlotte Suppli Ulrik

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The Australian & New Zealand journal of obstetrics & gynaecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emilie Johanne Vedtofte HaastrupRespiratory Research Unit Hvidovre (REAC-H), Department of Respiratory Medicine, Copenhagen University Hospital-Hvidovre, Hvidovre, Denmark.
Esther Bay SmedegaardRespiratory Research Unit Hvidovre (REAC-H), Department of Respiratory Medicine, Copenhagen University Hospital-Hvidovre, Hvidovre, Denmark.
Anne Vejen HansenRespiratory Research Unit Hvidovre (REAC-H), Department of Respiratory Medicine, Copenhagen University Hospital-Hvidovre, Hvidovre, Denmark.
Charlotte Suppli UlrikRespiratory Research Unit Hvidovre (REAC-H), Department of Respiratory Medicine, Copenhagen University Hospital-Hvidovre, Hvidovre, Denmark.ORCID https://orcid.org/0000-0001-8689-3695

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimPoor control of maternal asthma during pregnancy may increase the risk of pregnancy complications and adverse perinatal outcomes. The present review provides an update on the current knowledge of the association between asthma control during pregnancy and pregnancy complications, which are pre-eclampsia, low birth weight (LBW), pre-term birth, and small for gestational age (SGA).

methodsThis review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.

resultsA total of 14 studies fulfilled the predefined criteria for inclusion in the present review. The included studies revealed that the presence of maternal asthma per se is associated with an increased risk of SGA, whereas the observations were contradictory in relation to pre-eclampsia, LBW and pre-term birth. Asthma exacerbations and uncontrolled asthma during pregnancy were associated with an increased risk of pre-eclampsia. The studies did, however, not consistently suggest an increased risk of LBW, pre-term birth or SGA associated with asthma exacerbations during pregnancy.

conclusionsApart from small for gestational age, maternal asthma itself is not associated with a higher risk of pregnancy complications and adverse perinatal outcomes. However, asthma exacerbations and uncontrolled asthma during pregnancy increase the risk of pre-eclampsia.

Indexed as

AsthmaPre-EclampsiaPregnancy ComplicationsPremature BirthFemaleHumansInfant, Low Birth WeightInfant, NewbornInfant, Small for Gestational AgePregnancyPregnancy Outcomeasthmaasthma controlpregnancy complications

Identifiers

PMID41913695
PMCPMC13036474

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.