Evidence map›Paper›PMID 41913583›Full record

ArticleEuropean journal of pain (London, England)2026

Longitudinal Associations Among Pain Catastrophizing, Pain Interference, and Pain Medication Use in Adolescents With Chronic Pain.

Juan P Sanabria-Mazo, Josep Roman-Juan, Mark P Jensen, Jordi Miró

Abstract read
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Article in European journal of pain (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Juan P Sanabria-MazoUnit for the Study and Treatment of Pain-ALGOS, Department of Psychology, Research Center for Behavior Assessment (CRAMC), Universitat Rovira i Virgili, Tarragona, Spain.ORCID https://orcid.org/0000-0003-1688-435X
Josep Roman-JuanDepartment of Psychology, University of Calgary, Calgary, Canada.ORCID https://orcid.org/0000-0003-3383-5226
Mark P JensenDepartment of Rehabilitation Medicine, University of Washington, Seattle, WA, USA.ORCID https://orcid.org/0000-0003-3392-9767
Jordi MiróUnit for the Study and Treatment of Pain-ALGOS, Department of Psychology, Research Center for Behavior Assessment (CRAMC), Universitat Rovira i Virgili, Tarragona, Spain.ORCID https://orcid.org/0000-0002-1998-6653

Funding

European Regional Development FundInstitució Catalana de Recerca i Estudis AvançatsInternational Association for the Study of PainMinistry of Economy
6 · The paper itself

Abstract

backgroundCross-sectional studies have reported associations between pain catastrophizing and pain medication use in youth with chronic pain; however, the factors underlying this association remain unclear. Guided by the paediatric Fear-Avoidance model, this cohort study examined whether pain interference played a role in the longitudinal association between pain catastrophizing and subsequent pain medication use.

methodsParticipants were drawn from the EPIDOL project and included 180 adolescents (mean age = 13.56 years; 78% female) with chronic pain at both first assessment (T1) and 12-month follow-up (T2). Self-report measures assessed demographics (birth sex and age), pain characteristics (location, extent, and intensity), pain interference, pain catastrophizing, and pain medication use. Generalized structural equation models tested theory-guided autoregressive and cross-lagged panel specifications. Models adjusted for age, birth sex, and pain intensity and accounted for temporal stability.

resultsPain catastrophizing and pain medication use showed moderate to high temporal stability. No significant association was observed between pain catastrophizing at T1 and pain medication use at T2. In contrast, pain interference at T1 was significantly associated with pain medication use at T2, even when controlling for pain catastrophizing at T1. Findings were consistent across model specifications.

conclusionsThe findings suggest that pain interference may represent a functional factor prospectively associated with subsequent pain medication use. Future research should examine its potential role in linking pain catastrophizing and pain medication use when such associations are observed. Overall, the results support assessing both cognitive and functional dimensions when evaluating pain-related management patterns in youth with chronic pain. SIGNIFICANCE STATEMENT: This longitudinal study found that the association between pain catastrophizing and pain medication use inadolescents with chronic pain was accounted for indirectly by pain interference. These findings highlight theimportance of addressing both functional interference and pain-related cognitions in paediatric pain management.

Indexed as

AnalgesicsCatastrophizationChronic PainAdolescentFemaleHumansLongitudinal StudiesMalePain MeasurementAnalgesics

Identifiers

PMID41913583
PMCPMC13036390

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