Evidence map›Paper›PMID 41913341›Full record

SynthesisThe International journal of eating disorders2026

A Systematic Review and Meta-Analysis of Psychological Therapies for Avoidant/Restrictive Food Intake Disorder (ARFID) in Adolescents and Adults.

Copeland G Winten, Esben Strodl, P Evelyna Kambanis, Lynda J Ross, Jennifer J Thomas

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in The International journal of eating disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Copeland G WintenSchool of Exercise and Nutrition Science, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0001-9132-1982
Esben StrodlSchool of Psychology and Counselling, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0002-7149-6395
P Evelyna KambanisEating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-1950-3332
Lynda J RossSchool of Exercise and Nutrition Science, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0003-2947-4130
Jennifer J ThomasEating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0003-2601-581X

Funding

Mentorship in Biobehavioral Mechanisms of Avoidant/Restrictive Food Intake DisorderK24MH135189 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI JENNIFER JOANNE THOMAS · 2023 to 2026
$747k
Development and testing of a mobile app to scale delivery of cognitive- behavioral therapy for avoidant/restrictive food intake disorderK23MH139989 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI Paraskevi Evelyna Kambanis · 2025 to 2026
$395k
Australian Government Research Training Program ScholarshipNIMH NIH HHS K23 MH139989NIMH NIH HHS K24 MH135189NIMH NIH HHS K24MH135189Rubenstein Charitable Foundation
6 · The paper itself

Abstract

objectiveThe efficacy of psychological therapies for adolescents and adults with avoidant/restrictive food intake disorder (ARFID) has yet to be rigorously analyzed through systematic review or meta-analysis.

methodWe identified articles from seven databases that presented psychological therapies for adolescents and adults with ARFID. First, our systematic review explored characteristics of psychological interventions, clinical team composition, changes in dietary intake, and methodological quality. Second, we conducted a meta-analysis to quantify effect sizes for two primary outcomes (ARFID psychopathology and weight gain) and two secondary outcomes (anxiety and depression) from pretreatment to posttreatment.

resultsForty articles included in the systematic review identified a variety of psychological interventions that led to increased dietary variety. Most studies were of high quality. Of these, 17 articles met the inclusion criteria for the meta-analysis. Across studies, adolescents and adults with ARFID showed significant improvements from pretreatment to posttreatment including medium-size reductions in ARFID psychopathology (g = 0.63, p < 0.001), large increases in weight (g = 1.26, p < 0.001), medium-size reductions in anxiety (g = 0.42, p < 0.001), and small reductions in depression (g = 0.34, p < 0.05). DISCUSSION: This systematic review and meta-analysis highlights promising preliminary outcomes of psychological therapies for adolescents and adults with ARFID across multiple domains. However, the current evidence base is small and primarily reliant on case studies and case series, with very few quasi-experimental or randomized designs. As such, studies with larger sample sizes utilizing randomized control trial designs are needed to provide a more rigorous evaluation of psychological therapies for ARFID.

Indexed as

Avoidant Restrictive Food Intake DisorderPsychosocial InterventionPsychotherapyAdolescentAdultHumansTreatment OutcomeadultsARFIDavoidant/restrictive food intake disordercognitive‐behavioral therapyfamily‐based treatmentfeeding and eating disordersmeta‐analysissystematic reviewtherapyadolescents

Identifiers

PMID41913341
PMCPMC13326795

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.