Evidence map›Paper›PMID 41913338›Full record

ArticleEuropean journal of immunology2026

Dynamic Thymic Stromal Lymphopoietin and Its Receptor Complex Expression on Skin Langerhans Cells in Response to MC903-induced Skin Inflammation.

Martín I González-Rodríguez, Tanja Salomaa, Carolina Cabalin, Tuomas Komulainen, Lotta Hiihtola, Laura Kummola, Tero A H Järvinen, Ilkka S Junttila

Abstract read
In one paragraph

Article in European journal of immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Martín I González-RodríguezFaculty of Medicine and Health Technology, Tampere University (TUNI), Tampere, Finland.ORCID 0000-0001-9434-0636
Tanja SalomaaFaculty of Medicine and Health Technology, Tampere University (TUNI), Tampere, Finland.ORCID 0000-0003-4213-3066
Carolina CabalinInverSkin SpA, Santiago, Chile.ORCID 0000-0001-6344-3966
Tuomas KomulainenFaculty of Medicine and Health Technology, Tampere University (TUNI), Tampere, Finland.ORCID 0009-0006-5709-8645
Lotta HiihtolaFaculty of Medicine and Health Technology, Tampere University (TUNI), Tampere, Finland.ORCID 0000-0002-4144-3559
Laura KummolaFaculty of Medicine and Health Technology, Tampere University (TUNI), Tampere, Finland.ORCID 0000-0003-3285-3668
Tero A H JärvinenFaculty of Medicine and Health Technology, Tampere University (TUNI), Tampere, Finland.ORCID 0000-0002-4027-1759
Ilkka S JunttilaFaculty of Medicine and Health Technology, Tampere University (TUNI), Tampere, Finland.ORCID 0000-0002-9830-0823

Funding

Academy of Finland 3121369146Allergy Research FoundationCompetitive State Research Financing of Expert Responsibility Area of Fimlab Laboratories X51409Finnish Concordia FundFinnish Cultural FoundationFinnish Medical Foundation 6397National Research and Development Agency 21181854Nordlab KT0016Päivikki and Sakari Sohlberg FoundationSigrid Juselius FoundationState funding for university-level health research and TAUHTampere Tuberculosis FoundationTAUH Support FoundationWellbeing services county of Pirkanmaa T62774Wellbeing services county of Pirkanmaa T62904Wellbeing services county of Pirkanmaa T63764
6 · The paper itself

Abstract

Thymic Stromal Lymphopoietin (TSLP) regulates the skin microenvironment during type 2 inflammation. Epidermal APCs, Langerhans cells (LCs), might be the target of TSLP, but whether LCs express CD127 needed for TSLP signaling has been unclear. We found that LCs express both receptor chains needed by TSLP (CD127 and TSLPR) and upregulate the TSLPR upon Calcipotriol (MC903)-induced inflammation.

Indexed as

CalcitriolCytokinesImmunoglobulinsLangerhans CellsReceptors, CytokineSkinAnimalsHumansInflammationMiceReceptors, Interleukin-7Signal TransductionThymic Stromal LymphopoietincalcipotrieneCalcitriolCytokinesImmunoglobulinsinterleukin-7 receptor, alpha chainReceptors, CytokineReceptors, Interleukin-7Thymic Stromal LymphopoietinTslpr protein, mouseLangerhans cellsTSLP

Identifiers

PMID41913338
PMCPMC13036299

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.