Evidence map›Paper›PMID 41912981›Full record

ArticleCardiovascular engineering and technology2026

Shape and Scale in Quantifying Aortic Morphology Evolution and Chronicity.

Joseph A Pugar, David Jiang, Junsung Kim, Luka Pocivavsek

Abstract read
In one paragraph

Article in Cardiovascular engineering and technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joseph A PugarDepartment of Surgery, University of Chicago, 5801 S Ellis Ave, Chicago, IL, 60637, USA.ORCID 0000-0003-3295-5664
David JiangDepartment of Surgery, University of Chicago, 5801 S Ellis Ave, Chicago, IL, 60637, USA.
Junsung KimDepartment of Surgery, University of Chicago, 5801 S Ellis Ave, Chicago, IL, 60637, USA.
Luka PocivavsekDepartment of Surgery, University of Chicago, 5801 S Ellis Ave, Chicago, IL, 60637, USA. lpocivavsek@bsd.uchicago.edu.

Funding

NIH HHS NHLBI Grant R01-HL15920
6 · The paper itself

Abstract

purposeDecision-making in thoracic aortic disease primarily relies on diameter thresholds that compress rich three-dimensional morphology into a single length scale. Intrinsic shape measures have been shown to complement diameter, but their utility depends critically on the observation scale imposed during quantification. We aim to identify scales at which a size-invariant shape descriptor, specifically the normalized fluctuation in total integrated Gaussian curvature

methodsWe construct a scale space of aortic surface representations from CTA images via a factorial sweep across smoothing intensity, mesh density, and mesh partitioning (coarse-graining) size. For each construction we compute

resultsA reproducible stable zone emerges in which centimeter-scale partitioning consistently maximizes the informativeness of

conclusionOptimizing scale space yields a tuned, size-invariant shape signal that is both robust and clinically interpretable. The observed association between

Indexed as

Aorta, ThoracicAortographyComputed Tomography AngiographyDissection, Thoracic AortaRadiographic Image Interpretation, Computer-AssistedAortic Aneurysm, ThoracicChronic DiseaseDisease ProgressionHumansPredictive Value of TestsReproducibility of ResultsChronicityCT imagingScale spaceShapeThoracic aorta

Identifiers

PMID41912981
PMCPMC13260104

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.