ArticleJournal of general internal medicine2026
Correlates of COVID-19 Vaccine Regret in the United States.
Article in Journal of general internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
9 authors.
Funding
Abstract
backgroundDespite a wealth of COVID-19 vaccine hesitancy research, few researchers have measured post-COVID-19 vaccine regret or its associations with other health-related attitudes and behaviors.
objectiveTo measure participants' COVID-19 vaccination status, the prevalence of post-vaccination regret, and associated health-related attitudes and intentions.
designOnline national survey in April (n = 2,036) and an online national longitudinal survey in June-July 2024 (n = 1,454).
participantsUS adults aged 18 and older. MAIN MEASURE: The primary outcome is a three-item measure of COVID-19 vaccine regret. KEY
resultsApproximately 15% of US respondents who received at least one dose of the COVID-19 vaccine, consistent across surveys, expressed regret. Regret was negatively associated with vaccine-related behavioral intentions and with social and institutional trust. Vaccine regret was positively associated with a desire to discourage others from vaccinating, support for anti-vaccine politicians, and beliefs in health-related conspiracy theories. Individuals who had been required to be vaccinated were more likely to regret vaccination than those who were not, though this effect is isolated to respondents who would not have vaccinated otherwise.
conclusionsVaccine regret is associated with numerous health-related beliefs and behaviors. To prevent the social contagion of regret, public health institutions should consider messaging campaigns targeting the vaccinated as well as the unvaccinated. Public health researchers should be wary of using vaccine status as a proxy for hesitancy or future intentions, as regret may deter vaccinated individuals from future vaccinations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.