Evidence map›Paper›PMID 41912896›Full record

ArticleNature cell biology2026

Reinvigorating COTL1

Wenhua You, Chupeng Hu, Yuhan Zhang, Yedi Huang, Jianzhou Yuan, Cai-Yuan Wu, Deyuan Kong, Mengya Zhao, Yueqing Han, Songmao Li and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature cell biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Loss of NCCRP1 overcomes immune evasion in lung adenocarcinoma.Journal for immunotherapy of cancer · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Wenhua You *Department of Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Nanjing, China.
Chupeng Hu *Department of Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Nanjing, China.
Yuhan ZhangDepartment of Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Nanjing, China.
Yedi HuangDepartment of Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Nanjing, China.
Jianzhou YuanDepartment of Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Nanjing, China.
Cai-Yuan WuGuangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Deyuan KongDepartment of Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Nanjing, China.
Mengya ZhaoDepartment of Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Nanjing, China.
Yueqing HanDepartment of Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Nanjing, China.
Songmao LiDepartment of Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Nanjing, China.
Ruimin ShanDepartment of Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Nanjing, China.
Jinying LuDepartment of Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Nanjing, China.
Ming ChengInstitute of Modern Biology, Nanjing University, Nanjing, China.
Qing LiHepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Key Laboratory of Liver Transplantation, Chinese Academy of Medical Sciences, NHC Key Laboratory of Living Donor Liver Transplantation, Nanjing Medical University, Nanjing, China.
Bin YaoNational Experimental Teaching Center of Basic Medical Science, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, China.ORCID http://orcid.org/0000-0002-6657-2760
Xiao-Fang YuCancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0002-8748-7186
Qing XiaDepartment of Oncology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. xiaqing@shsmu.edu.cn.ORCID http://orcid.org/0000-0002-7001-5908
Wei ChongDepartment of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China. chongwei@sdfmu.edu.cn.ORCID http://orcid.org/0000-0002-1074-8595
Dong-Ming KuangGuangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, School of Life Sciences, Sun Yat-sen University, Guangzhou, China. kdming@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0003-3570-9717
Yun ChenDepartment of Immunology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Nanjing, China. chenyun@njmu.edu.cn.ORCID http://orcid.org/0000-0002-4118-362X

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82230059,U25A20111National Natural Science Foundation of China (National Science Foundation of China) 82573130
6 · The paper itself

Abstract

Patients with impaired tumour-specific major histocompatibility complex class I (tsMHC-I

Indexed as

Drug Resistance, NeoplasmGlucocorticoid-Induced TNFR-Related ProteinHistocompatibility Antigens Class IImmune Checkpoint InhibitorsKiller Cells, NaturalNeoplasmsAnimalsB7-H1 AntigenCell Line, TumorHumansImmunological SynapsesLymphocyte ActivationMacrophagesMiceSignal TransductionB7-H1 AntigenCD274 protein, humanGlucocorticoid-Induced TNFR-Related ProteinHistocompatibility Antigens Class IImmune Checkpoint InhibitorsTNFRSF18 protein, human

Identifiers

PMID41912896
PMCPMC13179135

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.