Evidence map›Paper›PMID 41912819›Full record

ArticleDoklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections2026

Generation of Stra8-Cre/ERT2 Mouse Activator Strain for Inducible Cre-lox Recombination in Spermatocytes.

L A Ilchuk, M V Kubekina, Yu D Okulova, E N Korshunov, M A Filatov, A V Bruter, Yu Yu Silaeva

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Article in Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

L A IlchukInstitute of Gene Biology, Russian Academy of Sciences, Moscow, Russia.
M V KubekinaInstitute of Gene Biology, Russian Academy of Sciences, Moscow, Russia.
Yu D OkulovaInstitute of Gene Biology, Russian Academy of Sciences, Moscow, Russia.
E N KorshunovInstitute of Gene Biology, Russian Academy of Sciences, Moscow, Russia.
M A FilatovInstitute of Gene Biology, Russian Academy of Sciences, Moscow, Russia.
A V BruterInstitute of Gene Biology, Russian Academy of Sciences, Moscow, Russia.
Yu Yu SilaevaInstitute of Gene Biology, Russian Academy of Sciences, Moscow, Russia. yulyasilaeva@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reverse genetics often requires systems that allow intended induction of toxic genes or inactivation of vital genes at a chosen moment and/or in a chosen tissue. Cre-lox recombination is a common tool of genetic engineering and is used to conditionally knock out a gene, in which an exon is preliminarily flanked with loxP sites, or to induce expression of a gene, in which a loxP-flanked STOP cassette is preliminarily inserted between the promoter and the open reading frame. A mouse strain, Stra8-Cre/ER

Indexed as

Adaptor Proteins, Signal TransducingIntegrasesRecombination, GeneticSpermatocytesAnimalsMaleMeiosisMiceMice, TransgenicPromoter Regions, GeneticTamoxifenAdaptor Proteins, Signal TransducingCre recombinaseIntegrasesStra8 protein, mouseTamoxifenCre-lox recombinationmeiosisspermatocytestransgenic mice

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.