Evidence map›Paper›PMID 41912530›Full record

ArticleNature communications2026

Early life bacteria and sibling exposure associate with restoration of the infant gut microbiome after cesarean section.

Jie Jiang, Casper Sahl Poulsen, Ulrika Boulund, Shiraz Shah, Urvish Trivedi, Madhumita Bhattacharyya, Avidan U Neumann, Darlene L Y Dai, Charisse Petersen, Courtney Hoskinson and 11 more

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [Gut microbiota and allergic diseases].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Jie JiangCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark.
Casper Sahl PoulsenCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark.
Ulrika BoulundCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark.
Shiraz ShahCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark.ORCID 0000-0002-4665-577X
Urvish TrivediCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark.ORCID 0000-0003-1541-6212
Madhumita BhattacharyyaInstitute of Environmental Medicine and Integrative Health, Faculty of Medicine, University of Augsburg, Augsburg, Germany.
Avidan U NeumannInstitute of Environmental Medicine and Integrative Health, Faculty of Medicine, University of Augsburg, Augsburg, Germany.
Darlene L Y DaiDepartment of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada.ORCID 0009-0002-0997-0639
Charisse PetersenDepartment of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0003-4045-2610
Courtney HoskinsonDepartment of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0001-8637-6022
Theo J MoraesDepartment of Pediatrics, The Hospital for Sick Children, Toronto, Canada.ORCID 0000-0001-9968-6601
Piushkumar J MandhaneDepartment of Pediatrics, University of Alberta, Edmonton, Canada.
Elinor SimonsSection of Allergy and Immunology, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada.
Meghan B AzadSection of Allergy and Immunology, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada.ORCID 0000-0002-5942-4444
Padmaja SubbaraoDepartment of Pediatrics, The Hospital for Sick Children, Toronto, Canada.ORCID 0000-0003-0394-1933
Klaus BønnelykkeCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark.ORCID 0000-0003-2003-1018
Bo ChawesCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark.ORCID 0000-0001-6846-6243
Stuart E TurveyDepartment of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada.
Søren J SørensenDepartment of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-6227-9906
Jonathan ThorsenCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark.ORCID 0000-0003-0200-0461
Jakob StokholmCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark. stokholm@copsac.com.ORCID 0000-0003-4989-9769

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long-term gut microbiome perturbation following Cesarean section (CS) delivery has been associated with an increased risk of developing childhood asthma. Whether such CS-associated microbiome composition can be modulated by environmental exposures or ecological interactions, and thereby mitigate disease risk, is unclear. In the COPSAC

Indexed as

AsthmaBacteriaCesarean SectionGastrointestinal MicrobiomeSiblingsBirth CohortCanadaFecesFemaleHumansInfantInfant, NewbornPregnancy

Identifiers

PMID41912530
PMCPMC13194679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.