Evidence map›Paper›PMID 41912520›Full record

ArticleNature communications2026

AI-guided multi-omics analysis identifies NPC1-modulated susceptibility to SARS-CoV-2 infection under PM

Guoqing Feng, Zheng Dong, Limei Ke, Weilai Zhou, Yu Tian, Xingtian Li, Wenxin Xiang, Yanjun Li, Qi Huang, Linfeng Liu and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Guoqing FengSchool of Biomedical Engineering, Tsinghua University, Beijing, China.
Zheng DongMedical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China. don1105@126.com.ORCID http://orcid.org/0009-0008-5210-7455
Limei KeSchool of Public Health, Soochow University, Suzhou, China.ORCID http://orcid.org/0000-0002-5030-6716
Weilai ZhouSchool of Public Health, China Medical University, Shenyang, China.ORCID http://orcid.org/0009-0004-3339-1172
Yu TianSchool of Basic Medical Sciences, Tsinghua University, Beijing, China.
Xingtian LiDivision of Sports Science and Physical Education, Tsinghua University, Beijing, China.
Wenxin XiangSchool of Biomedical Engineering, Tsinghua University, Beijing, China.
Yanjun LiVanke School of Public Health, Tsinghua University, Beijing, China.
Qi HuangVanke School of Public Health, Tsinghua University, Beijing, China.
Linfeng LiuSchool of Biomedical Engineering, Tsinghua University, Beijing, China.
Bo YinSchool of Biomedical Engineering, Tsinghua University, Beijing, China.ORCID http://orcid.org/0009-0006-3327-0084
Shouyi YanSchool of Biomedical Engineering, Tsinghua University, Beijing, China.
Jianxiu LiuDivision of Sports Science and Physical Education, Tsinghua University, Beijing, China.
Xindong MaDivision of Sports Science and Physical Education, Tsinghua University, Beijing, China.
Huaiyong ChenKey Laboratory of Lung Regenerative Medicine, Haihe Hospital, Tianjin University, Tianjin, China.ORCID http://orcid.org/0000-0002-1201-0535
Miao HeSchool of Public Health, China Medical University, Shenyang, China.
Ke HaoCollege of Environmental Science and Engineering, Tongji University, Shanghai, China.
Sijin LiuMedical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.ORCID http://orcid.org/0000-0002-5643-0734
Qian DiVanke School of Public Health, Tsinghua University, Beijing, China. qiandi@tsinghua.edu.cn.ORCID http://orcid.org/0000-0002-1584-4770

Funding

National Natural Science Foundation of China (National Science Foundation of China) 42077396National Natural Science Foundation of China (National Science Foundation of China) 42277419National Natural Science Foundation of China (National Science Foundation of China) 81773394
6 · The paper itself

Abstract

Exposure to airborne fine particulate matter (PM

Indexed as

COVID-19Niemann-Pick C1 ProteinParticulate MatterSARS-CoV-2Genetic Predisposition to DiseaseGenome-Wide Association StudyHumansMultiomicsTranscriptomeVirus InternalizationNiemann-Pick C1 ProteinParticulate Matter

Identifiers

PMID41912520
PMCPMC13194984

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.