Evidence map›Paper›PMID 41912359›Full record

ArticleNeuropathology and applied neurobiology2026

MR-Guided Laser Interstitial Thermal Therapy for Recurrent Glioblastoma: A Case Report With Novel Insights Into Histopathological Changes and Immunological Responses.

Silas Haahr Nielsen, Sara Blaabjerg Artzi, Jane Skjøth-Rasmussen, Carl Christian Larsen, Nadine Margaretha Hammouda, Karen Bonde Larsen, Rune Rasmussen, Adam Espe Hansen, Bjarne Winther Kristensen

Abstract readCase Reports
In one paragraph

Article in Neuropathology and applied neurobiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Laser interstitial thermal therapy in pediatric neurosurgery: a prospective nationwide study on indications, safety, and early outcomes.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Silas Haahr NielsenDepartment of Neurosurgery, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.ORCID 0000-0003-3417-2444
Sara Blaabjerg ArtziDanish Comprehensive Cancer Center, Brain Tumor Center, Copenhagen, Denmark.ORCID 0000-0002-4641-9128
Jane Skjøth-RasmussenDepartment of Neurosurgery, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Carl Christian LarsenDepartment of Neurosurgery, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Nadine Margaretha HammoudaDanish Comprehensive Cancer Center, Brain Tumor Center, Copenhagen, Denmark.
Karen Bonde LarsenDanish Comprehensive Cancer Center, Brain Tumor Center, Copenhagen, Denmark.
Rune RasmussenDepartment of Neurosurgery, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Adam Espe HansenDanish Comprehensive Cancer Center, Brain Tumor Center, Copenhagen, Denmark.
Bjarne Winther KristensenDanish Comprehensive Cancer Center, Brain Tumor Center, Copenhagen, Denmark.

Funding

Copenhagen University Hospital, RigshospitaletDanish Cancer Society R295-A16770
6 · The paper itself

Abstract

MR-guided laser interstitial thermal therapy (LITT) offers a minimally invasive option for recurrent glioblastoma, but human post-treatment tissue data are scarce. In this case report, post-LITT tissue exhibited distinct zonal changes, including central necrosis within the ablation zone and reduced tumour proliferation with increased CD8

Indexed as

Brain NeoplasmsGlioblastomaLaser TherapyNeoplasm Recurrence, LocalAdultHumansMagnetic Resonance ImagingMaleglioblastomaimmune responseMR‐guided laser interstitial thermal therapyneurosurgeryrecurrencestereotactic laser ablationtumour microenvironment

Identifiers

PMID41912359
PMCPMC13035459

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.