Evidence map›Paper›PMID 41912204›Full record

ArticleDermatology practical & conceptual2026

Distal Nail Canal Visible on Onychoscopy as a Diagnostic Sign of Dermatophytoma.

Luca Rapparini, Stephano Cedirian, Francesca Pampaloni, Francesca Bruni, Federico Quadrelli, Aurora Alessandrini, Bianca Maria Piraccini, Michela Starace

Abstract read
In one paragraph

Article in Dermatology practical & conceptual, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luca RappariniDermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Stephano CedirianDermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Francesca PampaloniDermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Francesca BruniDermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Federico QuadrelliDermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Aurora AlessandriniDermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Bianca Maria PiracciniDermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Michela StaraceDermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly recognition of dermatophytoma is essential to initiating appropriate therapy and avoiding treatment failure. Dermatophytoma is a variant of distal subungual onychomycosis, characterized by an accumulation of hyphae and scales trapped under the nail plate, making antifungal treatment challenging. Its hallmark feature is a yellow-white mass under the nail with a distal band of onycholysis or "canal".

objectivesThis study aimed to describe the clinical and onychoscopic features of dermatophytoma to improve diagnostic accuracy.

methodsWe conducted a retrospective study of 16 dermatophytoma cases diagnosed from 2020 to 2024 in a Nail Disorders Outpatient Clinic. Inclusion criteria were clinical and onychoscopic diagnosis, microbiological confirmation, and availability of dermoscopic images. Demographic, clinical, microbiological, and dermoscopic data were analyzed descriptively.

resultsFifteen patients (with 16 dermatophytomas) were included (8 males, 7 females; mean age 67.9 ± 14.2 years). The big toe was most frequently affected (87.5%). Trichophyton rubrum was the predominant pathogen (94%). Onychoscopy revealed yellow discoloration in all cases, with multicolored lesions in 81.3%. Most lesions were oval (56%) or elongated (25%), with an average transverse diameter of 5.6 ± 2.9 mm. A characteristic distal "canal" of onycholysis was identified in all cases, most commonly linear or wavy.

conclusionsOnychoscopy reveals specific features, particularly the presence of a canal, that can aid early diagnosis. Recognizing these features is essential to initiating combined antifungal and mechanical therapy to improve outcomes. Training clinicians to identify the canal sign may significantly enhance diagnostic accuracy and therapeutic success.

Identifiers

PMID41912204
PMCPMC12952826

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.