ArticleDermatology practical & conceptual2026
Dermoscopic Assessment of Nail Alterations in Egyptian Patients with Alopecia Areata.
Article in Dermatology practical & conceptual, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionAlopecia areata (AA) is an autoimmune disorder characterized by non-scarring hair loss. Hair and nails have many commonalities related to their development and structure and both can be involved in a range of disorders. Dermoscopy is a valuable noninvasive diagnostic tool that enhances clinical evaluation and treatment monitoring by detecting subtle nail changes not visible to the naked eye.
aimThe goals of this study were to assess the prevalence and types of various fingernail changes in patients with alopecia areata using dermoscopy and to compare the findings with those observed in healthy controls.
methodsA case-control study was conducted including 120 patients diagnosed with alopecia areata and 120 healthy individuals as controls. Dermoscopic examination of the fingernails was done for all participants. The severity of alopecia areata was evaluated using the Severity of Alopecia Tool (SALT) score.
resultsNail changes were observed in 78.3% of patients with alopecia areata, compared to only 14.2% in the control group, showing a statistically significant difference (P<0.05). The most frequent dermoscopic nail change was nail pitting (59%), followed by dry scales on the lateral nail fold (28.3%), scaly cuticle (18.3%), punctate leukonychia (17.5%), onychoschizia (14.2%), and longitudinal ridging (13.3%). There was a significant association between nail changes and disease severity, patient age, and alopecia areata duration.
conclusionsNail changes are common in patients with alopecia areata and may serve as valuable prognostic indicators for disease severity.
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