ArticleDermatology practical & conceptual2026
Risk Factors for Pediatric Alopecia Areata: Clinical and Biochemical Findings from a Case - Control Study.
Article in Dermatology practical & conceptual, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAlopecia areata (AA) is an immune-mediated, non-scarring hair loss disorder that can begin in childhood. Data on comorbidities and biochemical risk factors in pediatric AA remain limited.
objectivesTo compare clinical comorbidities and biochemical parameters in pediatric patients with AA versus healthy controls.
methodsThis retrospective, matched case-control study included 200 pediatric AA patients and 400 age- and sex-matched healthy controls. Clinical characteristics and comorbidities were obtained from patient records. Hemoglobin, ferritin, vitamin B12, and thyroid-stimulating hormone (TSH) levels were analyzed. Independent predictors were identified using multivariable logistic regression.
resultsVitiligo (3.5% vs. 0.5%; P=0.008), allergic asthma (9.5% vs. 3.8%; P=0.007), and attention-deficit/hyperactivity disorder (ADHD) (3.5% vs. 0.5%; P=0.008) were significantly more frequent in the AA group, whereas atopic dermatitis was more common but not statistically significant. Hemoglobin levels were comparable. Serum vitamin B12 [233.5 (192.7-270.0) vs. 356.7 (318.7-396.8) pg/mL; P<0.001] and ferritin [14.4 (6.5-22.3) vs. 19.4 (11.6-27.0) ng/mL; P<0.001] were significantly lower, and TSH levels were also reduced (3.40 ± 1.48 vs. 3.71 ± 1.50 mIU/L; P=0.017). Multivariable analysis identified low vitamin B12 (OR = 0.964, 95% CI: 0.958-0.970; P<0.001) and low ferritin (OR = 0.965, 95% CI: 0.944-0.988; P=0.003) as independent risk factors.
conclusionsPediatric AA is associated with vitiligo, asthma, ADHD, and reduced levels of ferritin, vitamin B12, and TSH. These findings underscore the importance of comprehensive clinical and biochemical evaluation in pediatric AA.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.